Automatic Detection and Scoring of Kidney Stones on Noncontrast CT Images Using S.T.O.N.E. Nephrolithometry: Combined Deep Learning and Thresholding Methods.

Purpose: To develop and validate a deep learning and thresholding-based model for automatic kidney stone detection and scoring according to S.T.O.N.E. nephrolithometry.Procedures: Abdominal noncontrast computed tomography (NCCT) images were retrospectively archived from February 2018 to April 2019 f...

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Publicado en:Molecular Imaging & Biology Vol. 23; no. 3; pp. 436 - 446
Autores principales: Cui, Yingpu, Sun, Zhaonan, Ma, Shuai, Liu, Weipeng, Wang, Xiangpeng, Zhang, Xiaodong, Wang, Xiaoying
Formato: Journal Article
Publicado: Springer Nature Jun2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2021
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s11307-020-01554-0
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        atl: Automatic Detection and Scoring of Kidney Stones on Noncontrast CT Images Using S.T.O.N.E. Nephrolithometry: Combined Deep Learning and Thresholding Methods.
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          Cui, Yingpu
          Sun, Zhaonan
          Ma, Shuai
          Liu, Weipeng
          Wang, Xiangpeng
          Zhang, Xiaodong
          Wang, Xiaoying
        affil: Department of Radiology, Peking University First Hospital, 8, Xishiku Street, Xicheng District, 100034, Beijing, China
      sug:
        subj:
          Information Science
          Kidney Calculi
          Tomography, X-Ray Computed Methods
          Predictive Value of Tests
          Severity of Illness Indices
          Aged
          Retrospective Design
          Contrast Media
          Female
          Middle Age
          Algorithms
          Imaging, Three-Dimensional
          Pharmacokinetics
          Male
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Purpose: To develop and validate a deep learning and thresholding-based model for automatic kidney stone detection and scoring according to S.T.O.N.E. nephrolithometry.Procedures: Abdominal noncontrast computed tomography (NCCT) images were retrospectively archived from February 2018 to April 2019 for three parts: a segmentation dataset (n = 167), a hydronephrosis classification dataset (n = 282), and test dataset (n = 117). The model consisted of four steps. First, the 3D U-Nets for kidney and renal sinus segmentation were developed. Second, the deep 3D dual-path networks for hydronephrosis grading were developed. Third, the thresholding methods were used to detect and segment stones in the renal sinus region. The stone size, CT attenuation, and tract length were calculated from the segmented stone region. Fourth, the stone's location was determined. The stone detection performance was estimated with sensitivity and positive predictive value (PPV). The hydronephrosis grading and stone size, tract length, number of involved calyces, and essence grading were estimated with the area under the curve (AUC) method and linear-weighted κ statistics, respectively.Results: The stone detection algorithm reached a sensitivity of 95.9 % (236/246) and a PPV of 98.7 % (236/239). The hydronephrosis classification algorithm achieved an AUC of 0.97. The scoring model results showed good agreement with radiologist results for the stone size, tract length, number of involved calyces, and essence grading (κ = 0.95, 95 % confidence interval [CI]: 0.92, 0.98; κ = 0.97, 95 % CI: 0.95, 1.00; κ = 0.95, 95 % CI: 0.92, 0.98; and κ = 0.97, 95 % CI: 0.94, 1.00), respectively.Conclusions: The scoring model was constructed that can automatically detect and score stones in NCCT images.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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