Ventricular pre‐excitation in primary care patients: Evaluation of the risk of mortality.

Background: Ventricular pre‐excitation is characterized by the presence of atrioventricular accessory pathways, predisposing to arrhythmias. Although it is well established that risk stratification in symptomatic patients should be invasive, there is a lack of evidence of the benefit in asymptomatic...

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Publicado en:Journal of Cardiovascular Electrophysiology Vol. 32; no. 5; pp. 1290 - 1296
Autores principales: Paixão, Gabriela M. M., Lima, Emilly M., Batista, Luisa M., Santos, Luis Felipe, Araujo, Sabrina L. O., Araujo, Rodrigo M., Oliveira, Derick M., Nascimento, Jamil S., Gomes, Paulo R., Ribeiro, Antonio L.
Formato: research tables/charts tracings Journal Article
Publicado: Wiley-Blackwell May2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2021
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Ventricular pre‐excitation in primary care patients: Evaluation of the risk of mortality.
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          Paixão, Gabriela M. M.
          Lima, Emilly M.
          Batista, Luisa M.
          Santos, Luis Felipe
          Araujo, Sabrina L. O.
          Araujo, Rodrigo M.
          Oliveira, Derick M.
          Nascimento, Jamil S.
          Gomes, Paulo R.
          Ribeiro, Antonio L.
        affil: Telehealth Center, Telehealth Network of Minas Gerais, Hospital das Clínicas and Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte Minas Gerais,, Brazil
      sug:
        subj:
          Primary Health Care
          Electrocardiography
          Mortality Risk Factors
          Wolff-Parkinson-White Syndrome
          Risk Assessment
          Human
          Brazil
          Nonexperimental Studies
          Cox Proportional Hazards Model
          Regression
          Confidence Intervals
          Cardiologists
          Middle Age
          Male
          Female
          Multivariate Analysis
          Middle Aged: 45-64 years
          Male
          Female
      ab: Background: Ventricular pre‐excitation is characterized by the presence of atrioventricular accessory pathways, predisposing to arrhythmias. Although it is well established that risk stratification in symptomatic patients should be invasive, there is a lack of evidence of the benefit in asymptomatic. Objective: Evaluate ventricular pre‐excitation in the electrocardiogram (ECG) as a risk factor for overall mortality in patients of Telehealth Network of Minas Gerais (TNMG), Brazil. Methods: This observational study was developed with the database of digital ECGs (2010–2017) from TNMG. The electronic cohort was obtained by linking data from ECG exams and those from the national mortality information system. Only the first ECG was considered. Clinical data were self‐reported, and ECGs were interpreted manually by cardiologists and automatically by the Glasgow University Interpreter software. Hazard ratio (HR) for mortality was estimated using weighted Cox regression. Results: Nearly 1 665 667 patients were included (median age: 50 [Q1: 34; Q3: 63] years; 41.4% were male). In a mean follow‐up of 3.7 years, the overall mortality rate was 3.1%. The prevalence of ventricular pre‐excitation was 0.07%. In multivariate analysis, adjusting for sex and age, ventricular pre‐excitation was not associated with an increased risk of mortality (HR: 1.41; 95% confidence interval [CI]: 0.56–3.57; p =.47) when compared to the whole sample or to patients with normal ECG (HR: 1.41; 95% CI: 0.53–4.36; p =.43). In a subanalysis on accessory pathway location, there was no evidence of a higher risk of death related to any location. Conclusion: Ventricular pre‐excitation was not associated with an increased risk of mortality in a primary care cohort.
      pubtype: Academic Journal
      doctype:
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        tables/charts
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        Journal Article
      ougenre: Article
    language: English
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