Dynamic brain effective connectivity analysis based on low-rank canonical polyadic decomposition: application to epilepsy.

In this paper, a new method to track brain effective connectivity networks in the context of epilepsy is proposed. It relies on the combination of partial directed coherence with a constrained low-rank canonical polyadic tensor decomposition. With such combination being established, the most dominat...

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Publicado en:Medical & Biological Engineering & Computing Vol. 59; no. 5; pp. 1081 - 1099
Autores principales: Chantal, Pierre-Antoine, Karfoul, Ahmad, Nica, Anca, Le Bouquin Jeannès, Régine
Formato: Journal Article
Publicado: Springer Nature May2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2021
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s11517-021-02325-x
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        atl: Dynamic brain effective connectivity analysis based on low-rank canonical polyadic decomposition: application to epilepsy.
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          Chantal, Pierre-Antoine
          Karfoul, Ahmad
          Nica, Anca
          Le Bouquin Jeannès, Régine
        affil: Univ Rennes, Inserm, LTSI-UMR 1099, F-35000, Rennes, France
      sug:
        subj:
          Epilepsy
          Brain
          Brain Mapping
          Seizures
          Electroencephalography
          Scales
      ab: In this paper, a new method to track brain effective connectivity networks in the context of epilepsy is proposed. It relies on the combination of partial directed coherence with a constrained low-rank canonical polyadic tensor decomposition. With such combination being established, the most dominating directed graph structures underlying each time window of intracerebral electroencephalographic signals are optimally inferred. Obtained time and frequency signatures of inferred brain networks allow respectively to track the time evolution of these networks and to define frequency bands on which they are operating. Besides, the proposed method allows also to track brain connectivity networks through several epileptic seizures of the same patient. Understanding the most dominating directed graph structures over epileptic seizures and investigating their behavior over time and frequency plans are henceforth possible. Since only few but the the most important directed connections in the graph structure are of interest and also for a meaningful interpretation of obtained signatures to be guaranteed, the low-rank canonical polyadic tensor decomposition is prompted respectively by the sparsity and the non-negativity constraints on the tensor loading matrices. The main objective of this contribution is to propose a new way of tracking brain networks in the context of epileptic iEEG data by identifying the most dominant effective connectivity patterns underlying the observed iEEG signals at each time window. The performance of the proposed method is firstly evaluated on simulated data imitating brain activities and secondly on real intracerebral electroencephalographic signals obtained from an epileptic patient. The partial directed coherence-based tensor has been decomposed into space, time, and frequency signatures in accordance with the expected ground truth for each consecutive sequence of the simulated data. The method is also in accordance with the clinical expertise for iEEG epileptic signals, where the signatures were investigated through a simultaneous multi-seizure analysis.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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