Deep learning model for predicting gestational age after the first trimester using fetal MRI.

Objectives: To evaluate a deep learning model for predicting gestational age from fetal brain MRI acquired after the first trimester in comparison to biparietal diameter (BPD).Materials and Methods: Our Institutional Review Board approved this retrospective study, and a total of 184 T2-weighted MRI...

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Publicado en:European Radiology Vol. 31; no. 6; pp. 3775 - 3783
Autores principales: Kojita, Yasuyuki, Matsuo, Hidetoshi, Kanda, Tomonori, Nishio, Mizuho, Sofue, Keitaro, Nogami, Munenobu, Kono, Atsushi K., Hori, Masatoshi, Murakami, Takamichi
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Springer Nature Jun2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2021
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00330-021-07915-9
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        atl: Deep learning model for predicting gestational age after the first trimester using fetal MRI.
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        au:
          Kojita, Yasuyuki
          Matsuo, Hidetoshi
          Kanda, Tomonori
          Nishio, Mizuho
          Sofue, Keitaro
          Nogami, Munenobu
          Kono, Atsushi K.
          Hori, Masatoshi
          Murakami, Takamichi
        affil: Department of Radiology, Kobe University School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, 650-0017, Kobe, Hyogo, Japan
      sug:
        subj:
          Prenatal Care
          Gestational Age
          Female
          Ultrasonography, Prenatal
          Pregnancy Trimester, First
          Infant
          Pregnancy
          Retrospective Design
          Fetus
          Magnetic Resonance Imaging
          Infant: 1-23 months
          Fetus, conception to birth
          Female
      ab: Objectives: To evaluate a deep learning model for predicting gestational age from fetal brain MRI acquired after the first trimester in comparison to biparietal diameter (BPD).Materials and Methods: Our Institutional Review Board approved this retrospective study, and a total of 184 T2-weighted MRI acquisitions from 184 fetuses (mean gestational age: 29.4 weeks) who underwent MRI between January 2014 and June 2019 were included. The reference standard gestational age was based on the last menstruation and ultrasonography measurements in the first trimester. The deep learning model was trained with T2-weighted images from 126 training cases and 29 validation cases. The remaining 29 cases were used as test data, with fetal age estimated by both the model and BPD measurement. The relationship between the estimated gestational age and the reference standard was evaluated with Lin's concordance correlation coefficient (ρc) and a Bland-Altman plot. The ρc was assessed with McBride's definition.Results: The ρc of the model prediction was substantial (ρc = 0.964), but the ρc of the BPD prediction was moderate (ρc = 0.920). Both the model and BPD predictions had greater differences from the reference standard at increasing gestational age. However, the upper limit of the model's prediction (2.45 weeks) was significantly shorter than that of BPD (5.62 weeks).Conclusions: Deep learning can accurately predict gestational age from fetal brain MR acquired after the first trimester.Key Points: • The prediction of gestational age using ultrasound is accurate in the first trimester but becomes inaccurate as gestational age increases. • Deep learning can accurately predict gestational age from fetal brain MRI acquired in the second and third trimester. • Prediction of gestational age by deep learning may have benefits for prenatal care in pregnancies that are underserved during the first trimester.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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