Comparison of cervical cancer screening by self-sampling papillomavirus test versus pap-smear in underprivileged women in France.
Background: The purpose of this study was to compare cervical cancer screening by pap smear (PS) versus preliminary HPV testing based on self-collected samples (SC-HPV).Methods: Interventional study among underprivileged women from 25 to 65 years old in four French cities. The control group (CG) was...
| Publicado en: | BMC Women's Health Vol. 21; no. 1; pp. 1 - 15 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
BioMed Central
5/26/2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=150516834&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 150516834 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14726874 1CIP jtl: BMC Women's Health issn: 14726874 maglogo: N pubinfo: dt: 5/26/2021 vid: 21 iid: 1 pid: 24147 pub: BioMed Central artinfo: ui: 150516834 150516834 NLM34039341 150516834 10.1186/s12905-021-01356-8 NLM34039341 150516834 ppf: 1 ppct: 14 formats: fmt: @attributes: type: P tig: atl: Comparison of cervical cancer screening by self-sampling papillomavirus test versus pap-smear in underprivileged women in France. aug: au: Reques, Laura Rolland, Camille Lallemand, Anne Lahmidi, Najat Aranda-Fernández, Ezequiel Lazzarino, Antonio Bottero, Julie Hamers, Françoise Bergeron, Christine Haguenoer, Ken Launoy, Guy Luhmann, Niklas affil: Médecins du Monde, 62 rue Marcadet, 75018, Paris, France sug: subj: Papillomavirus Infections Diagnosis Cervix Neoplasms Diagnosis Middle Age Early Detection of Cancer Cervical Smears France Adult Health Screening Aged Female Papillomaviruses Human Comparative Studies Multicenter Studies Evaluation Research Validation Studies Middle Aged: 45-64 years Adult: 19-44 years Aged: 65+ years Female ab: Background: The purpose of this study was to compare cervical cancer screening by pap smear (PS) versus preliminary HPV testing based on self-collected samples (SC-HPV).Methods: Interventional study among underprivileged women from 25 to 65 years old in four French cities. The control group (CG) was referred for a PS. The experimental group (EG) conducted a SC-HPV test followed by a PS in case of positivity. Differences on screening completion and cytological abnormalities were analysed by logistic and Cox regression.Results: 383 women were assigned to the EG and 304 to the CG. The screening completion proportion was 39.5% in the CG compared to 71.3% in the EG (HR = 2.48 (CI 95% [1.99-3.08]; p < 0.001). The proportion of cytological abnormalities was 2.0% in the CG and 2.3% in the EG (OR = 1.20 (CI 95% [0.42-3.40]; p = 0.7). The proportion of participants lost to follow-up was 60.5% in the CG and 63.2% in the EG HPV positive (p = 0.18).Conclusion: Providing an SC-HPV-test increased the participation of underprivileged women in CCS. Nevertheless, the significant number of lost to follow-up in both groups can undermine the initial benefits of the strategy for HPV positive women. Registration: Clinicaltrials.gov: NCT03118258. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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