Development and double cross-validation of new spot urine sodium equation to predict 24-h urine sodium in the Malaysian population.

Background: Monitoring sodium intake through 24-h urine collection sample is recommended, but the implementation of this method can be difficult. The objective of this study was to develop and validate an equation using spot urine concentration to predict 24-h sodium excretion in the Malaysian popul...

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Publicado en:Journal of Health, Population & Nutrition Vol. 40; pp. 1 - 9
Autores principales: Othman, Fatimah, Ambak, Rashidah, Omar, Mohd Azahadi, Shahar, Suzana, Nor, Noor Safiza Mohd, Ahmad, Mohamad Hasnan, Yusoff, Muhammad Fadhli Mohd, Haron, Hasnah, Noh, Mohd Fairulnizal Md, Aris, Tahir
Formato: research Journal Article
Publicado: BioMed Central 5/31/2021 Supplement 1
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 5/31/2021 Supplement 1
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      pub: BioMed Central
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        10.1186/s41043-021-00232-3
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        atl: Development and double cross-validation of new spot urine sodium equation to predict 24-h urine sodium in the Malaysian population.
      aug:
        au:
          Othman, Fatimah
          Ambak, Rashidah
          Omar, Mohd Azahadi
          Shahar, Suzana
          Nor, Noor Safiza Mohd
          Ahmad, Mohamad Hasnan
          Yusoff, Muhammad Fadhli Mohd
          Haron, Hasnah
          Noh, Mohd Fairulnizal Md
          Aris, Tahir
        affil: Institute for Public Health, National Institutes of Health, Ministry of Health Malaysia, Shah Alam, Selangor, Malaysia
      sug:
        subj:
          Sodium
          Sodium, Dietary
          Urinalysis
          Multivariate Analysis
          Human
          Urine Specimen Collection
          Comparative Studies
          Multicenter Studies
          Evaluation Research
          Validation Studies
      ab: Background: Monitoring sodium intake through 24-h urine collection sample is recommended, but the implementation of this method can be difficult. The objective of this study was to develop and validate an equation using spot urine concentration to predict 24-h sodium excretion in the Malaysian population.Methods: This was a Malaysian Community Salt Study (MyCoSS) sub-study, which was conducted from October 2017 to March 2018. Out of 798 participants in the MyCoSS study who completed 24-h urine collection, 768 of them have collected one-time spot urine the following morning. They were randomly assigned into two groups to form separate spot urine equations. The final spot urine equation was derived from the entire data set after confirming the stability of the equation by double cross-validation in both study groups. Newly derived spot urine equation was developed using the coefficients from the multiple linear regression test. A Bland-Altman plot was used to measure the mean bias and limits of agreement between estimated and measured 24-h urine sodium. The estimation of sodium intake using the new equation was compared with other established equations, namely Tanaka and INTERSALT.Results: The new equation showed the least mean bias between measured and predicted sodium, - 0.35 (- 72.26, 71.56) mg/day compared to Tanaka, 629.83 (532.19, 727.47) mg/day and INTERSALT, and 360.82 (284.34, 437.29) mg/day. Predicted sodium measured from the new equation showed greater correlation with measured sodium (r = 0.50) compared to Tanaka (r =0.24) and INTERSALT (r = 0.44), P < 0.05.Conclusion: Our newly developed equation from spot urine can predict least mean bias of sodium intake among the Malaysian population when 24-h urine sodium collection is not feasible.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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