Applying Intravenous Immunoglobulin and Negative-Pressure Wound Therapy to Treat Refractory Pyoderma Gangrenosum: A Case Report.
Pyoderma gangrenosum (PG) is a rare chronic neutrophilic dermatosis that causes undermining ulcers. Unfortunately, standardization of PG treatment remains a challenge. In this article, we describe a case in which a 69-year-old man presented with a painful ulcer on the right lower leg. The diagnosis...
| Publicado en: | International Journal of Lower Extremity Wounds Vol. 20; no. 2; pp. 158 - 162 |
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| Autores principales: | , , , |
| Formato: | case study pictorial tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
Jun2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=150796026&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 150796026 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15347346 IYG jtl: International Journal of Lower Extremity Wounds issn: 15347346 maglogo: Y pubinfo: dt: Jun2021 vid: 20 iid: 2 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 150796026 146269539 150796026 150796026 10.1177/1534734620940459 150796026 ppf: 158 ppct: 4 formats: tig: atl: Applying Intravenous Immunoglobulin and Negative-Pressure Wound Therapy to Treat Refractory Pyoderma Gangrenosum: A Case Report. aug: au: Jin, Shi-Ying Chen, Mei Wang, Feng-Yuan Wang, Fei affil: Zhongda Hospital, Southeast University, Nanjing, Jiangsu, China sug: subj: Immunoglobulins Administration and Dosage Administration, Intravenous Negative Pressure Wound Therapy Pyoderma Gangrenosum Therapy Immunosuppression Aged Male Methylprednisolone Therapeutic Use Cyclosporins Therapeutic Use Thalidomide Therapeutic Use Sulfasalazine Therapeutic Use Dexamethasone Therapeutic Use Aged: 65+ years Male ab: Pyoderma gangrenosum (PG) is a rare chronic neutrophilic dermatosis that causes undermining ulcers. Unfortunately, standardization of PG treatment remains a challenge. In this article, we describe a case in which a 69-year-old man presented with a painful ulcer on the right lower leg. The diagnosis of PG was made after excluding other diseases. He had a history of PG on his left lower leg 2 years earlier and was cured by the treatment of systemic corticosteroids and cyclosporin A for 43 days. However, such a treatment was not effective this time. Hence, we applied intravenous immunoglobulin and negative-pressure wound therapy, and the patient was cured. Altogether, this case supports the use of intravenous immunoglobulin as an effective adjuvant for refractory PG, and indicates negative-pressure wound therapy as a treatment option to advance ulcer healing under adequate immunosuppression. pubtype: Academic Journal doctype: case study pictorial tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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