Using a risk model for probability of cancer in pulmonary nodules.

Background: Considering the high morbidity and mortality of lung cancer and the high incidence of pulmonary nodules, clearly distinguishing benign from malignant lung nodules at an early stage is of great significance. However, determining the kind of lung nodule which is more prone to lung cancer r...

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Publicado en:Thoracic Cancer Vol. 12; no. 12; pp. 1881 - 1890
Autores principales: Liu, Si‐Qi, Ma, Xiao‐Bin, Song, Wan‐Mei, Li, Yi‐Fan, Li, Ning, Wang, Li‐Na, Liu, Jin‐Yue, Tao, Ning‐Ning, Li, Shi‐Jin, Xu, Ting‐Ting, Zhang, Qian‐Yun, An, Qi‐Qi, Liang, Bin, Li, Huai‐Chen
Formato: algorithm research tables/charts Journal Article
Publicado: Wiley-Blackwell Jun2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2021
      vid: 12
      iid: 12
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        150889103
        150224325
        150889103
        150889103
        10.1111/1759-7714.13991
        150889103
      ppf: 1881
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        atl: Using a risk model for probability of cancer in pulmonary nodules.
      aug:
        au:
          Liu, Si‐Qi
          Ma, Xiao‐Bin
          Song, Wan‐Mei
          Li, Yi‐Fan
          Li, Ning
          Wang, Li‐Na
          Liu, Jin‐Yue
          Tao, Ning‐Ning
          Li, Shi‐Jin
          Xu, Ting‐Ting
          Zhang, Qian‐Yun
          An, Qi‐Qi
          Liang, Bin
          Li, Huai‐Chen
        affil: Department of Respiratory and Critical Care Medicine, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China
      sug:
        subj:
          Lung Pathology
          Lung Neoplasms Risk Factors
          Risk Assessment Methods
          Models, Theoretical
          Human
          China
          Radiography, Thoracic
          Tomography, X-Ray Computed
          Thoracic Surgery, Video-Assisted
          Pneumonectomy Methods
          Machine Learning
          Algorithms
          Decision Trees
          Early Detection of Cancer
          Cancer Screening
      ab: Background: Considering the high morbidity and mortality of lung cancer and the high incidence of pulmonary nodules, clearly distinguishing benign from malignant lung nodules at an early stage is of great significance. However, determining the kind of lung nodule which is more prone to lung cancer remains a problem worldwide. Methods: A total of 480 patients with pulmonary nodule data were collected from Shandong, China. We assessed the clinical characteristics and computed tomography (CT) imaging features among pulmonary nodules in patients who had undergone video‐assisted thoracoscopic surgery (VATS) lobectomy from 2013 to 2018. Preliminary selection of features was based on a statistical analysis using SPSS. We used WEKA to assess the machine learning models using its multiple algorithms and selected the best decision tree model using its optimization algorithm. Results: The combination of decision tree and logistics regression optimized the decision tree without affecting its AUC. The decision tree structure showed that lobulation was the most important feature, followed by spiculation, vessel convergence sign, nodule type, satellite nodule, nodule size and age of patient. Conclusions: Our study shows that decision tree analyses can be applied to screen individuals for early lung cancer with CT. Our decision tree provides a new way to help clinicians establish a logical diagnosis by a stepwise progression method, but still needs to be validated for prospective trials in a larger patient population.
      pubtype: Academic Journal
      doctype:
        algorithm
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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