Risk of Aerosol Formation During High-Flow Nasal Cannula Treatment in Critically Ill Subjects.
BACKGROUND: There is a persistent concern over the risk of respiratory pathogen transmission, including SARS-CoV-2, via the formation of aerosols (ie, a suspension of microdroplets and residual microparticles after evaporation) generated during high-flow nasal cannula (HFNC) oxygen therapy in critic...
| Publicado en: | Respiratory Care Vol. 66; no. 6; pp. 891 - 897 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Jun2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=150953531&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 150953531 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Jun2021 vid: 66 iid: 6 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 150953531 150953531 150953531 10.4187/respcare.08756 150953531 ppf: 891 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Risk of Aerosol Formation During High-Flow Nasal Cannula Treatment in Critically Ill Subjects. aug: au: Bem, Reinout A. van Mourik, Niels Klein-Blommert, Rozalinde Spijkerman, Ingrid JB Kooij, Stefan Bonn, Daniel Vlaar, Alexander P. affil: Department of Pediatric Intensive Care, Emma Children's Hospital, Amsterdam University Medical Centers, Amsterdam, The Netherlands sug: subj: Critically Ill Patients Oxygen Therapy Methods Nasal Cannula Aerosols Disease Transmission Risk Factors Risk Assessment Human Cross Infection Risk Factors COVID-19 Respiratory Distress Syndrome, Acute Pneumonia Descriptive Statistics Repeated Measures Analysis of Variance Post Hoc Analysis Fisher's Exact Test Mann-Whitney U Test Data Analysis Software ab: BACKGROUND: There is a persistent concern over the risk of respiratory pathogen transmission, including SARS-CoV-2, via the formation of aerosols (ie, a suspension of microdroplets and residual microparticles after evaporation) generated during high-flow nasal cannula (HFNC) oxygen therapy in critically ill patients. This concern is fueled by limited available studies on this subject. In this study, we tested our hypothesis that HFNC treatment is not associated with increased aerosol formation as compared to conventional oxygen therapy. METHODS: We used laser light scattering and a handheld particle counter to detect and quantify aerosols in healthy subjects and in adults with acute respiratory disease, including COVID-19, during HFNC or conventional oxygen therapy. RESULTS: The use of HFNC was not associated with increased formation of aerosols as compared to conventional oxygen therapy in both healthy subjects (n = 3) and subjects with acute respiratory disease, including COVID-19 (n = 17). CONCLUSIONS: In line with scarce previous clinical and experimental findings, our results indicate that HFNC itself does not result in overall increased aerosol formation as compared to conventional oxygen therapy. This suggests there is no increased risk of respiratory pathogen transmission to health care workers during HFNC. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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