IMI2-PainCare-BioPain-RCT3: a randomized, double-blind, placebo-controlled, crossover, multi-center trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by electroencephalography (EEG).

Background: IMI2-PainCare-BioPain-RCT3 is one of four similarly designed clinical studies aiming at profiling a set of functional biomarkers of drug effects on the nociceptive system that could serve to accelerate the future development of analgesics, by providing a quantitative understanding betwee...

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Bibliographic Details
Published in:Trials Vol. 22; no. 1; pp. 1 - 32
Main Authors: Mouraux, André, Bloms-Funke, Petra, Boesl, Irmgard, Caspani, Ombretta, Chapman, Sonya C., Di Stefano, Giulia, Finnerup, Nanna Brix, Garcia-Larrea, Luis, Goetz, Marcus, Kostenko, Anna, Pelz, Bernhard, Pogatzki-Zahn, Esther, Schubart, Karin, Stouffs, Alexandre, Truini, Andrea, Tracey, Irene, Troconiz, Iñaki F., Van Niel, Johannes, Vela, Jose Miguel, Vincent, Katy
Format: research randomized controlled trial Journal Article
Published: BioMed Central 6/17/2021
Online Access:View this record in EBSCOhost