Reduction of falls in a rat model of PD falls by the M1 PAM TAK-071.
Rationale: In addition to the disease-defining motor symptoms, patients with Parkinson's disease (PD) exhibit gait dysfunction, postural instability, and a propensity for falls. These dopamine (DA) replacement-resistant symptoms in part have been attributed to loss of basal forebrain (BF) cholinergi...
| Publicado en: | Psychopharmacology Vol. 238; no. 7; pp. 1953 - 1965 |
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| Autores principales: | , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Jul2021
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| Acceso en línea: | Ver este registro en EBSCOhost |