Effect of an 8-week Exercise Training on Gut Microbiota in Physically Inactive Older Women.

Exercise can alter the composition of gut microbiota. However, studies examining the effects of exercise on gut microbiota in the elderly are lacking. This study aims to investigate whether an 8-week exercise training affect gut microbiota in physically inactive elderly women. Fourteen women were ra...

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Publicado en:International Journal of Sports Medicine Vol. 42; no. 7; pp. 610 - 624
Autores principales: Zhong, Fei, Wen, Xu, Yang, Min, Lai, Hsin-Yi, Momma, Haruki, Cheng, Lei, Sun, Xiaomin, Nagatomi, Ryoichi, Huang, Cong
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Georg Thieme Verlag Stuttgart 2021
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Georg Thieme Verlag Stuttgart
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        10.1055/a-1301-7011
        151085775
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        atl: Effect of an 8-week Exercise Training on Gut Microbiota in Physically Inactive Older Women.
      aug:
        au:
          Zhong, Fei
          Wen, Xu
          Yang, Min
          Lai, Hsin-Yi
          Momma, Haruki
          Cheng, Lei
          Sun, Xiaomin
          Nagatomi, Ryoichi
          Huang, Cong
        affil: Department of Sports and Exercise Science, Zhejiang University, Hangzhou, China
      sug:
        subj:
          Training Effect (Physiology) Evaluation
          Resistance Training
          Exercise Physiology
          Gut Microbiota
          Time Factors
          Human
          Aged
          Randomized Controlled Trials
          Random Assignment
          Control Group
          Repeated Measures
          Analysis of Variance
          Comparative Studies
          Outcome Assessment
          Actinobacteria
          Aerobic Exercises
          Descriptive Statistics
          Aged: 65+ years
      ab: Exercise can alter the composition of gut microbiota. However, studies examining the effects of exercise on gut microbiota in the elderly are lacking. This study aims to investigate whether an 8-week exercise training affect gut microbiota in physically inactive elderly women. Fourteen women were randomly assigned to either exercise group or control group. Repeated-measures analysis of variance was used to reveal changes in gut microbiota. Alpha diversity did not change significantly. A tendency to form 2 clusters was observed for operational taxonomic units (OTU) after intervention. At phylum, class, and order levels, a significant difference was observed between two groups for Fusobacteria (F=5.257, P=0.045), Betaproteobacteria (F=5.149, P=0.047), and Bifidobacteriales (F=7.624, P=0.020). A significant interaction was observed between two groups for Actinobacteria (F=8.434, P=0.016). At family and genus levels, a significant main effect of groups was observed in Bifidobacteriaceae (F=7.624, P=0.020), Bifidobacterium (F=7.404, P=0.022), and Gemmiger (F=5.881, P=0.036). These findings indicate that an 8-week exercise training may induce partial changes in relative abundance and OTU clustering of gut microbiota in physically inactive elderly women. Also, exercise may increase the abundance of bacteria associated with anti-inflammation such as Verrucomicrobia, reduce the abundance of bacteria associated with pro-inflammation such as Proteobacteria
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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