Effect of noise and ototoxicants on developing standard threshold shifts at a U.S. Air Force depot level maintenance facility.

Noise exposure has traditionally been considered the primary risk factor for hearing loss. However, ototoxicants commonly found in occupational settings could affect hearing loss independently, additively, or synergistically when combined with noise exposures. The purpose of this investigation was t...

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Publicado en:Journal of Occupational & Environmental Hygiene Vol. 18; no. 7; pp. 323 - 334
Autores principales: Blair, Marc, Slagley, Jeremy, Schaal, N. Cody
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Jul2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2021
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      pub: Taylor & Francis Ltd
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        10.1080/15459624.2021.1922693
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        atl: Effect of noise and ototoxicants on developing standard threshold shifts at a U.S. Air Force depot level maintenance facility.
      aug:
        au:
          Blair, Marc
          Slagley, Jeremy
          Schaal, N. Cody
        affil: Department of Systems Engineering and Management, Air Force Institute of Technology, Wright-Patterson AFB, Ohio
      sug:
        subj:
          United States Air Force
          Noise Adverse Effects
          Occupational Exposure
          Hearing Disorders Risk Factors
          Human
          Audiometry, Pure-Tone
          Oklahoma
          Solvents
          Metals
          Comparative Studies
          Descriptive Statistics
          Confidence Intervals
      ab: Noise exposure has traditionally been considered the primary risk factor for hearing loss. However, ototoxicants commonly found in occupational settings could affect hearing loss independently, additively, or synergistically when combined with noise exposures. The purpose of this investigation was to determine the combined effect of metal and solvent ototoxicants, continuous noise, and impulse noise on hearing loss. Noise and ototoxicant exposure and pure-tone audiometry results were analyzed for U.S. Air Force personnel (n = 2,372) at a depot-level aircraft maintenance activity at Tinker Air Force Base, Oklahoma. Eight similar exposure groups based on combinations of ototoxicant and noise exposure were created including: (1) Continuous noise (reference group); (2) Continuous noise + Impulse noise; (3) Metal exposures + Continuous noise; (4) Metal exposures + Continuous noise + Impulse noise; (5) Solvent exposure + Continuous noise; (6) Solvent exposures + Continuous noise + Impulse noise; (7) Metal exposure + Solvent exposures + Continuous noise; and (8) Metal exposure + Solvent exposures + Continuous noise + Impulse noise. Hearing loss was assessed at center octave band frequencies of 500–6,000 Hz and using National Institute for Occupational Safety and Health Standard Threshold Shift (STS) criteria. Hearing changes were significantly worse at 2,000 Hz in the Metal exposure + Solvent exposure + Continuous noise group compared to the Continuous noise only reference group (p = 0.023). The Metal exposure + Solvent exposure + Continuous noise group had a significantly greater relative risk (RR) of 2.44; 95% CI [1.24, 4.83] for developing an STS at 2,000 Hz. While not statistically significant, the Solvent exposure + Continuous noise group had a RR of 2.32; 95%CI [1.00, 5.34] for developing an STS at 1,000 Hz. These results indicate that noise exposure may dominate hearing loss at ≥3,000 Hz while combined effects of concomitant exposure to ototoxic substances and noise are only noticeable at ≤2,000 Hz. These results also suggest combined exposures to ototoxicants and noise presents a greater hearing loss risk than just noise.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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