Development and Analytical Validation of a Reverse Transcription Droplet Digital PCR (RT-ddPCR) Assay for PD-L1 Transcripts in Circulating Tumor Cells.

BACKGROUND: PD-L1, an immune checkpoint protein, is an important biomarker for monitoring cancer patients during the administration of cancer immunotherapy. Droplet digital PCR (ddPCR), is a highly sensitive and accurate tool for the quantification of cancer biomarkers in liquid biopsy. We report th...

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Publicado en:Clinical Chemistry Vol. 67; no. 4; pp. 642 - 653
Autores principales: Strati, Areti, Zavridou, Martha, Economopoulou, Panagiota, Gkolfinopoulos, Stavros, Psyrri, Amanda, Lianidou, Evi
Formato: Journal Article
Publicado: Oxford University Press / USA Apr2021
Acceso en línea:Ver este registro en EBSCOhost