Development and Validation of a Magnetic Resonance Imaging-Based Machine Learning Model for TMJ Pathologies.

The purpose of this study was to propose a machine learning model and assess its ability to classify TMJ pathologies on magnetic resonance (MR) images. This retrospective cohort study included 214 TMJs from 107 patients with TMJ signs and symptoms. A radiomics platform was used to extract (Huiying M...

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Published in:BioMed Research International pp. 1 - 12
Main Authors: Orhan, Kaan, Driesen, Lukas, Shujaat, Sohaib, Jacobs, Reinhilde, Chai, Xiangfei
Format: diagnostic images research tables/charts Journal Article
Published: Wiley-Blackwell 7/6/2021
Online Access:View this record in EBSCOhost
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      dt: 7/6/2021
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2021/6656773
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        atl: Development and Validation of a Magnetic Resonance Imaging-Based Machine Learning Model for TMJ Pathologies.
      aug:
        au:
          Orhan, Kaan
          Driesen, Lukas
          Shujaat, Sohaib
          Jacobs, Reinhilde
          Chai, Xiangfei
        affil: OMFS IMPATH Research Group, Department of Imaging & Pathology, Faculty of Medicine, University of Leuven and Oral & Maxillofacial Surgery, University Hospitals Leuven, Leuven, Belgium
      sug:
        subj:
          Machine Learning
          Magnetic Resonance Imaging
          Temporomandibular Joint Diseases Diagnosis
          Prediction Models
          Instrument Validation
          Instrument Construction
          Temporomandibular Joint Diseases Classification
          Human
          Retrospective Design
          Prospective Studies
          China
          Mandibular Condyle Pathology
          Intervertebral Disk Displacement
          Algorithms
          Logistic Regression
          Random Forest
          Support Vector Machine
          Sensitivity and Specificity
          ROC Curve
          Validation Studies
      ab: The purpose of this study was to propose a machine learning model and assess its ability to classify TMJ pathologies on magnetic resonance (MR) images. This retrospective cohort study included 214 TMJs from 107 patients with TMJ signs and symptoms. A radiomics platform was used to extract (Huiying Medical Technology Co., Ltd., China) imaging features of TMJ pathologies, condylar bone changes, and disc displacements. Thereafter, different machine learning (ML) algorithms and logistic regression were implemented on radiomic features for feature selection, classification, and prediction. The following radiomic features included first-order statistics, shape, texture, gray-level cooccurrence matrix (GLCM), gray-level run length matrix (GLRLM), and gray-level size zone matrix (GLSZM). Six classifiers, including logistic regression (LR), random forest (RF), decision tree (DT), k -nearest neighbors (KNN), XGBoost, and support vector machine (SVM) were used for model building which could predict the TMJ pathologies. The performance of models was evaluated by sensitivity, specificity, and ROC curve. KNN and RF classifiers were found to be the most optimal machine learning model for the prediction of TMJ pathologies. The AUC, sensitivity, and specificity for the training set were 0.89 and 1, while those for the testing set were 0.77 and 0.74, respectively, for condylar changes and disc displacement, respectively. For TMJ condylar bone changes Large-Area High-Gray-Level Emphasis, Gray-Level Nonuniformity, Long-Run Emphasis Long-Run High-Gray-Level Emphasis, Flatness, and Volume features, while for TMJ disc displacements Average Intensity, Sum Average, Spherical Disproportion, and Entropy features, were selected. This study has proposed a machine learning model by KNN and RF analysis on TMJ MR images, which can be used to classify condylar changes and TMJ disc displacements.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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