| Sumario: | This article is part of the Topical Collection on Technology In this review, we provide a comprehensive description of the principles behind recent technological innovations, elucidate the current evidence, and point to specific fields of clinical care in which adoption of the most advanced technology, without careful thought, may put the previously established clinical role and benefits of PET at risk. PET/CT systems equipped with SiPM are commonly named "digital PET" although, strictly speaking, only SiPM with digital photon counting are fully digital [[36]]. PET in lung cancer In a prospective, randomized controlled trial, [ SP 18 sp F]fluorodeoxyglucose (FDG)-PET for staging patients with non-small cell lung cancer (NSCLC) revealed extensive mediastinal lymph node or distant metastases more frequently than conventional staging methods alone. New technologies for the purpose of this review comprise PET image reconstruction algorithms with point spread function (PSF) compensation and Bayesian penalized likelihood (PL) reconstruction algorithms as well as "digital PET" (i.e., using silicon photomultipliers (SiPM) instead of photomultiplier tubes (PMT)). 22899197 64 Hotta M, Minamimoto R, Yano H, Gohda Y, Shuno Y. Diagnostic performance of (18)F-FDG PET/CT using point spread function reconstruction on initial staging of rectal cancer: a comparison study with conventional PET/CT and pelvic MRI.
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