Clonotypic Features of Rearranged Immunoglobulin Genes Yield Personalized Biomarkers for Minimal Residual Disease Monitoring in Multiple Myeloma.

BACKGROUND: Due to improved treatment, more patients with multiple myeloma (MM) reach a state of minimal residual disease (MRD). Different strategies for MM MRD monitoring include flow cytometry, allele-specific oligonucleotide–quantitative PCR, next generation sequencing, and mass spectrometry (MS)...

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Bibliographic Details

Published in:	Clinical Chemistry Vol. 67; no. 6; pp. 867 - 876
Main Authors:	Langerhorst, Pieter, Brinkman, Arie B., VanDuijn, Martijn M., Wessels, Hans J. C. T., Groenen, Patricia J. T. A., Joosten, Irma, van Gool, Alain J., Gloerich, Jolein, Scheijen, Blanca, Jacobs, Joannes F. M.
Format:	Journal Article
Published:	Oxford University Press / USA Jun2021
Online Access:	View this record in EBSCOhost