Predictive performance of parent-metabolite population pharmacokinetic models of (S)-ketamine in healthy volunteers.

Purpose: The recent repurposing of ketamine as treatment for pain and depression has increased the need for accurate population pharmacokinetic (PK) models to inform the design of new clinical trials. Therefore, the objectives of this study were to externally validate available PK models on (S)-(nor...

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Publicado en:European Journal of Clinical Pharmacology Vol. 77; no. 8; pp. 1181 - 1193
Autores principales: Otto, M. E., Bergmann, K. R., Jacobs, G., van Esdonk, Michiel J.
Formato: research tables/charts Journal Article
Publicado: Springer Nature Aug2021
Acceso en línea:Ver este registro en EBSCOhost