Intravenous administration of LPS activates the kynurenine pathway in healthy male human subjects: a prospective placebo-controlled cross-over trial.

Background: Administration of lipopolysaccharide (LPS) from Gram-negative bacteria, also known as the human endotoxemia model, is a standardized and safe model of human inflammation. Experimental studies have revealed that peripheral administration of LPS leads to induction of the kynurenine pathway...

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Detalles Bibliográficos
Publicado en:Journal of Neuroinflammation Vol. 18; no. 1; pp. 1 - 12
Autores principales: Millischer, Vincent, Heinzl, Matthias, Faka, Anthi, Resl, Michael, Trepci, Ada, Klammer, Carmen, Egger, Margot, Dieplinger, Benjamin, Clodi, Martin, Schwieler, Lilly
Formato: research randomized controlled trial Journal Article
Publicado: BioMed Central 7/17/2021
Acceso en línea:Ver este registro en EBSCOhost