Motor synergies: Evidence for a novel motor signature in autism spectrum disorder.
In autism spectrum disorder (ASD), socio-communicative impairments and stereotypical behaviours are paralleled by sensorimotor deficits. Individuals with ASD show an altered selection of motor parameters, resulting in clumsy and fragmented actions. Here, we investigated inter-joint coordination and...
| Publicado en: | Cognition Vol. 213 |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Elsevier B.V.
Aug2021
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=151588927&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 151588927 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00100277 3H9 jtl: Cognition issn: 00100277 maglogo: N pubinfo: dt: Aug2021 vid: 213 pid: 1004 pub: Elsevier B.V. artinfo: ui: 151588927 151588927 NLM33715840 151588927 10.1016/j.cognition.2021.104652 NLM33715840 151588927 ppct: 1 formats: tig: atl: Motor synergies: Evidence for a novel motor signature in autism spectrum disorder. aug: au: Emanuele, M. Nazzaro, G. Marini, M. Veronesi, C. Boni, S. Polletta, G. D'Ausilio, A. Fadiga, L. affil: University of Ferrara, Department of Neuroscience and Rehabilitation, Ferrara, Italy sug: subj: Communication Kinematics Human Social Behavior Child Grip Strength Comparative Studies Multicenter Studies Evaluation Research Validation Studies Child: 6-12 years ab: In autism spectrum disorder (ASD), socio-communicative impairments and stereotypical behaviours are paralleled by sensorimotor deficits. Individuals with ASD show an altered selection of motor parameters, resulting in clumsy and fragmented actions. Here, we investigated inter-joint coordination and motor synergies as a potential substrate of motor control problems in ASD. Synergies enable co-controlling redundant motor degrees of freedom (DoF, e.g. joint angles, muscles) by mapping behavioural goals into a flexible and low-dimensional set of variables. This mechanism simplifies motor control and helps to find unambiguous solutions for motor tasks. In a reaching-grasping paradigm, children with ASD showed reduced coupling between DoF, which correlated with socio-communicative symptoms severity. Impaired synergies may help to frame well-established motor problems in ASD, including impaired motor sequencing and abnormal trial-to-trial motor variability. On the other hand, synergies also provide an effective and compact coding system of observed actions. Impaired synergies may thus jeopardize motor interaction by initiating bottom-up cascade effects, leading to pervasive impairments of social behaviour. Finally, we trained an automatic classification algorithm to distinguish between ASD and typically developing (TD) participants based on reaching-grasping kinematics. Classification accuracy reached up to 0.947. This result corroborates and expands previous accounts claiming that motor-based early recognition is feasible and effective in ASD. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|