Presence of microorganisms in children with pharyngotonsillitis and healthy controls: a prospective study in primary healthcare.

Purpose: Most studies on paediatric pharyngotonsillitis focus on group A streptococci. This study, however, analyses a broad spectrum of bacteria and viruses related to paediatric pharyngotonsillitis and evaluates their associated clinical symptoms and courses. Methods: This observational prospectiv...

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Publicado en:Infection Vol. 49; no. 4; pp. 715 - 725
Autores principales: Pallon, Jon, Sundqvist, Martin, Rööst, Mattias, Danielsson, Patrik, Neumark, Thomas, Skovbjerg, Susann, Svedin, Jonas, Hedin, Katarina
Formato: research tables/charts Journal Article
Publicado: Springer Nature Aug2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2021
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s15010-021-01595-9
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        atl: Presence of microorganisms in children with pharyngotonsillitis and healthy controls: a prospective study in primary healthcare.
      aug:
        au:
          Pallon, Jon
          Sundqvist, Martin
          Rööst, Mattias
          Danielsson, Patrik
          Neumark, Thomas
          Skovbjerg, Susann
          Svedin, Jonas
          Hedin, Katarina
        affil: Department of Clinical Sciences in Malmö, Family Medicine, Lund University, Malmö, Sweden
      sug:
        subj:
          Tonsillitis Microbiology
          Pharyngitis Microbiology
          Primary Health Care
          Human
          Child
          Prospective Studies
          Nonexperimental Studies
          Diaries
          Record Review
          Polymerase Chain Reaction
          Streptococcus
          Child: 6-12 years
      ab: Purpose: Most studies on paediatric pharyngotonsillitis focus on group A streptococci. This study, however, analyses a broad spectrum of bacteria and viruses related to paediatric pharyngotonsillitis and evaluates their associated clinical symptoms and courses. Methods: This observational prospective study in primary healthcare includes 77 children aged < 15 with a sore throat and 34 asymptomatic children, all of whom were sampled from the tonsils with an E-swab® for analysis with culture and PCR for 14 bacteria and 15 viruses. Patients were evaluated clinically, and their symptoms recorded in diaries for 10 days. Participants were followed up for 3 months by reviewing medical records. Results: A pathogen was detected in 86% of patients and in 71% of controls (P = 0.06). Bacteria were found in 69% of patients and 59% of controls (P = 0.3), and viruses in 36% and 26%, respectively (P = 0.3). Group A streptococci was the most common finding, with a prevalence of 49% and 32%, respectively (P = 0.1). Clinical signs were not useful for distinguishing pathogens. None of the controls and 16% of the patients reconsulted for a sore throat within 3 months. Conclusion: Bacteria were more common than viruses in both study groups. The high rate of pathogens in asymptomatic children interferes with diagnoses based on aetiology.
      pubtype: Academic Journal
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      ougenre: Article
    language: English
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