A Permissioned Blockchain-Based Clinical Trial Service Platform to Improve Trial Data Transparency.
The clinical research faces numerous challenges, from patient enrollment to data privacy concerns and regulatory requirements to spiraling costs. Blockchain technology has the potential to overcome these challenges, thus making clinical trials transparent and enhancing public trust in a fair and ope...
| Publicado en: | BioMed Research International pp. 1 - 23 |
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| Autores principales: | , , , |
| Formato: | computer program pictorial tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
7/30/2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=151663929&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 151663929 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 7/30/2021 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 151663929 151663929 151663929 10.1155/2021/5554487 151663929 ppf: 1 ppct: 22 formats: fmt: @attributes: type: P tig: atl: A Permissioned Blockchain-Based Clinical Trial Service Platform to Improve Trial Data Transparency. aug: au: Hang, Lei Kim, BumHwi Kim, KyuHyung Kim, DoHyeun affil: Shanghai Normal University Tianhua College, Shanghai 201815, China sug: subj: Blockchain Utilization Research Methodology Clinical Trials Data Analysis, Computer Assisted Data Security Study Design ab: The clinical research faces numerous challenges, from patient enrollment to data privacy concerns and regulatory requirements to spiraling costs. Blockchain technology has the potential to overcome these challenges, thus making clinical trials transparent and enhancing public trust in a fair and open process with all stakeholders because of its distinct features such as data immutability and transparency. This paper proposes a permissioned blockchain platform to ensure clinical data transparency and provides secure clinical trial-related solutions. We explore the core functionalities of blockchain applied to clinical trials and illustrate its general principle concretely. These clinical trial operations are automated using the smart contract, which ensures traceability, prevents a posteriori reconstruction, and securely automates the clinical trial. A web-based user interface is also implemented to visualize the data from the blockchain and ease the interaction with the blockchain network. A proof of concept is implemented on Hyperledger Fabric in the case study of clinical management for multiple clinical trials to demonstrate the designed approach's feasibility. Lastly, the experiment results demonstrate the efficiency and usability of the proposed platform. pubtype: Academic Journal doctype: computer program pictorial tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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