Heterogeneous Associative Plasticity in the Auditory Cortex Induced by Fear Learning – Novel Insight Into the Classical Conditioning Paradigm.

We used two-photon calcium imaging with single-cell and celltype resolution. Fear conditioning induced heterogeneous tuning shifts at single-cell level in the auditory cortex, with shifts both to CS+ frequency and to the control CS- stimulus frequency. We thus extend the view of simple expansion of...

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Publicado en:Physiological Research Vol. 70; no. 3; pp. 447 - 461
Autores principales: ZELENKA, Ondrej, NOVAK, Ondrej, BRUNOVA, Aneta, SYKA, Josef
Formato: Journal Article
Publicado: Institute of Physiology, Academy of Sciences of the Czech Republic Jun2021
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Heterogeneous Associative Plasticity in the Auditory Cortex Induced by Fear Learning – Novel Insight Into the Classical Conditioning Paradigm.
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          ZELENKA, Ondrej
          NOVAK, Ondrej
          BRUNOVA, Aneta
          SYKA, Josef
        affil: Department of Auditory Neuroscience, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czech Republic.
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      ab: We used two-photon calcium imaging with single-cell and celltype resolution. Fear conditioning induced heterogeneous tuning shifts at single-cell level in the auditory cortex, with shifts both to CS+ frequency and to the control CS- stimulus frequency. We thus extend the view of simple expansion of CS+ tuned regions. Instead of conventional freezing reactions only, we observe selective orienting responses towards the conditioned stimuli. The orienting responses were often followed by escape behavior.
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      doctype: Journal Article
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    language: English
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