Semantic Memory and Lexical Availability in Parkinson's Disease: A Statistical Learning Study.
Parkinson's disease (PD) is a neurodegenerative disorder that causes a progressive impairment in motor and cognitive functions. Although semantic fluency deficits have been described in PD, more specific semantic memory (SM) and lexical availability (LA) domains have not been previously addressed. H...
| Publicado en: | Frontiers in Aging Neuroscience Vol. 13; pp. 1 - 12 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Frontiers Media S.A.
7/30/2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=151700594&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 151700594 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 16634365 BG2U jtl: Frontiers in Aging Neuroscience issn: 16634365 maglogo: N pubinfo: dt: 7/30/2021 vid: 13 pid: 40038 pub: Frontiers Media S.A. artinfo: ui: 151700594 10.3389/fnagi.2021.697065 151700594 ppf: 1 ppct: 11 formats: tig: atl: Semantic Memory and Lexical Availability in Parkinson's Disease: A Statistical Learning Study. aug: au: Cardona, Juan F. Grisales-Cardenas, Johan S. Trujillo-Llano, Catalina Diazgranados, Jesús A. Urquina, Hugo F. Cardona, Sebastián Torres, Alejandra Torres, Liliana A. Gonzalez, Lina M. Jaramillo, Tania Cediel, Judith Oñate-Cadena, Nelcy Mateus-Ferro, Geral Marmolejo-Ramos, Fernando affil: Facultad de Psicología, Universidad del Valle, Santiago de Cali, Colombia sug: ab: Parkinson's disease (PD) is a neurodegenerative disorder that causes a progressive impairment in motor and cognitive functions. Although semantic fluency deficits have been described in PD, more specific semantic memory (SM) and lexical availability (LA) domains have not been previously addressed. Here, we aimed to characterize the cognitive performance of PD patients in a set of SM and LA measures and determine the smallest set of neuropsychological (lexical, semantic, or executive) variables that most accurately classify groups. Thirty early-stage non-demented PD patients (age 35–75, 10 females) and thirty healthy controls (age 36–76, 12 females) were assessed via general cognitive, SM [three subtests of the CaGi battery including living (i.e., elephant) and non-living things (i.e., fork)], and LA (eliciting words from 10 semantic categories related to everyday life) measures. Results showed that PD patients performed lower than controls in two SM global scores (picture naming and naming in response to an oral description). This impairment was particularly pronounced in the non-living things subscale. Also, the number of words in the LA measure was inferior in PD patients than controls, in both larger and smaller semantic fields, showing a more inadequate recall strategy. Notably, the classification algorithms indicated that the SM task had high classification accuracy. In particular, the denomination of non-living things had a classification accuracy of ∼80%. These results suggest that frontostriatal deterioration in PD leads to search strategy deficits in SF and the potential disruption in semantic categorization. These findings are consistent with the embodied view of cognition. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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