RetFluidNet: Retinal Fluid Segmentation for SD-OCT Images Using Convolutional Neural Network.

Age-related macular degeneration (AMD) is one of the leading causes of irreversible blindness and is characterized by fluid-related accumulations such as intra-retinal fluid (IRF), subretinal fluid (SRF), and pigment epithelial detachment (PED). Spectral-domain optical coherence tomography (SD-OCT)...

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Publicado en:Journal of Digital Imaging Vol. 34; no. 3; pp. 691 - 705
Autores principales: Sappa, Loza Bekalo, Okuwobi, Idowu Paul, Li, Mingchao, Zhang, Yuhan, Xie, Sha, Yuan, Songtao, Chen, Qiang
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Jun2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2021
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      pub: Springer Nature
      place: New York, New York
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        atl: RetFluidNet: Retinal Fluid Segmentation for SD-OCT Images Using Convolutional Neural Network.
      aug:
        au:
          Sappa, Loza Bekalo
          Okuwobi, Idowu Paul
          Li, Mingchao
          Zhang, Yuhan
          Xie, Sha
          Yuan, Songtao
          Chen, Qiang
        affil: School of Computer Science and Engineering, Nanjing University of Science and Technology, 200 Xiaolingwei, 210094, Nanjing, China
      sug:
        subj:
          Exudates and Transudates Physiopathology
          Retina Radiography
          Tomography, Optical Coherence Methods
          Retinal Diseases Classification
          Neural Networks (Computer)
          Models, Statistical
          Human
          Macular Degeneration Diagnosis
          Retinal Diseases Pathology
          Diagnosis, Eye Methods
          Technology
          Retinal Diseases Diagnosis
          Sensitivity and Specificity
          Descriptive Statistics
          Automation
          Early Diagnosis
          After Care
      ab: Age-related macular degeneration (AMD) is one of the leading causes of irreversible blindness and is characterized by fluid-related accumulations such as intra-retinal fluid (IRF), subretinal fluid (SRF), and pigment epithelial detachment (PED). Spectral-domain optical coherence tomography (SD-OCT) is the primary modality used to diagnose AMD, yet it does not have algorithms that directly detect and quantify the fluid. This work presents an improved convolutional neural network (CNN)-based architecture called RetFluidNet to segment three types of fluid abnormalities from SD-OCT images. The model assimilates different skip-connect operations and atrous spatial pyramid pooling (ASPP) to integrate multi-scale contextual information; thus, achieving the best performance. This work also investigates between consequential and comparatively inconsequential hyperparameters and skip-connect techniques for fluid segmentation from the SD-OCT image to indicate the starting choice for future related researches. RetFluidNet was trained and tested on SD-OCT images from 124 patients and achieved an accuracy of 80.05%, 92.74%, and 95.53% for IRF, PED, and SRF, respectively. RetFluidNet showed significant improvement over competitive works to be clinically applicable in reasonable accuracy and time efficiency. RetFluidNet is a fully automated method that can support early detection and follow-up of AMD.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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