Exploring neuropsychological and socio‐emotional task performance in anorexia nervosa: A cluster analytic approach.

Objective: The aim of this study was to characterise heterogeneity in neuropsychological and socio‐emotional task performance in young women with anorexia nervosa (AN) using hierarchical cluster analysis. Further, we aimed to test whether cognitive profiles were associated with differences in clinic...

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Publicado en:European Eating Disorders Review Vol. 29; no. 5; pp. 802 - 811
Autores principales: Kerr‐Gaffney, Jess, Halls, Daniel, Leppanen, Jenni, Tchanturia, Kate
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Sep2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2021
      vid: 29
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1002/erv.2851
        151754537
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        atl: Exploring neuropsychological and socio‐emotional task performance in anorexia nervosa: A cluster analytic approach.
      aug:
        au:
          Kerr‐Gaffney, Jess
          Halls, Daniel
          Leppanen, Jenni
          Tchanturia, Kate
        affil: Department of Psychological Medicine, King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, UK
      sug:
        subj:
          Task Performance and Analysis
          Neuropsychology
          Anorexia Nervosa Psychosocial Factors
          Women's Health
          Cognition Evaluation
          Psychopathology
          Functional Status
          Human
          Female
          Cluster Analysis
          Body Mass Index
          Disease Duration
          Eating Disorders
          Autism Spectrum Disorder
          Anxiety
          Depression
          Analysis of Variance
          Neuropsychological Tests
          Theory of Mind
          Emotions
          Anorexia Nervosa Drug Therapy
          Comorbidity
          Female
      ab: Objective: The aim of this study was to characterise heterogeneity in neuropsychological and socio‐emotional task performance in young women with anorexia nervosa (AN) using hierarchical cluster analysis. Further, we aimed to test whether cognitive profiles were associated with differences in clinical variables (body mass index, illness duration and age at diagnosis), psychopathology (eating disorder, autistic symptoms, anxiety and depression) and functional impairment. Method: Set‐shifting, central coherence and theory of mind abilities were measured in 118 women with acute or remitted AN. A hierarchical cluster analysis using Ward's method with a Euclidean distance measure was performed with the neuropsychological and socio‐emotional variables. Differences between clusters were assessed using ANOVAs. Results: Four clusters emerged, with significant differences in neuropsychological and socio‐emotional task performance. There were no significant differences between clusters in clinical variables, psychopathology or functional impairment, however, these analyses lacked power due to small cluster sizes. Conclusions: Our results demonstrate significant heterogeneity in cognitive profiles in AN, supporting a more personalised approach to treatment. Studies in larger samples are required to establish whether these variables map onto clinically significant differences in aetiology, clinical presentation, comorbidity patterns and/or treatment responses. Key points: Four clusters of participants emerged, with significant differences in neuropsychological (set‐shifting, central coherence) and socio‐emotional (theory of mind) task performance. The largest cluster showed average to above‐average performance across domains.Clusters did not differ on clinical variables, eating disorder and comorbid psychopathology scores or functional impairment.The findings suggest significant heterogeneity in neuropsychological and socio‐emotional performance in anorexia nervosa, supporting a more personalised approach to treatment.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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