CT for lymph node staging of Colon cancer: not only size but also location and number of lymph node count.
Purpose: To evaluate the diagnostic accuracy of imaging features to predict lymph node status of colon cancer using CT. Methods: This was a retrospective study from 2 tertiary hospitals in South Korea and Netherlands. 317 Colon cancer patients who underwent primary surgical treatment were included....
| Publicado en: | Abdominal Radiology Vol. 46; no. 9; pp. 4096 - 4106 |
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| Autores principales: | , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Sep2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=151776196&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 151776196 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2366004X JT14 jtl: Abdominal Radiology issn: 2366004X maglogo: N pubinfo: dt: Sep2021 vid: 46 iid: 9 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 151776196 150016532 10.1007/s00261-021-03057-0 151776196 ppf: 4096 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: CT for lymph node staging of Colon cancer: not only size but also location and number of lymph node count. aug: au: Hong, Eun Kyoung Landolfi, Federica Castagnoli, Francesca Park, Sae Jin Boot, Judith Van den Berg, Jose Lee, Jeong Min Beets-Tan, Regina affil: Department of Radiology, Netherlands Cancer Institute, Amsterdam, The Netherlands sug: ab: Purpose: To evaluate the diagnostic accuracy of imaging features to predict lymph node status of colon cancer using CT. Methods: This was a retrospective study from 2 tertiary hospitals in South Korea and Netherlands. 317 Colon cancer patients who underwent primary surgical treatment were included. Number of lymph nodes according to the anatomical location, size, cluster, degree of attenuation, shape, presence of internal heterogeneity and ill-defined margin of the lymph node were assessed and compared according to histological lymph node status. Results: The largest short diameter of lymph node and presence of internal heterogeneity of lymph node showed significant association with malignant lymph node status (P < 0.001 and P = 0.041, respectively). The ROC curve analysis revealed AUC of 0.703 for the largest short diameter of lymph node (P < 0.001), and AUC of the presence of internal heterogeneity was 0.630 (P < 0.001). In addition, our study showed that a total number of lymph nodes, regardless of size, (P = 0.022) and number of lymph nodes in peritumoral area (P < 0.001) and along the mesenteric vessels (P < 0.001) on CT demonstrated significant association with malignant status of lymph nodes in colon cancer. Conclusions: There were significant associations between lymph node status and imaging features of lymph nodes on CT in colon cancer patients. The largest short diameter of lymph node and presence of internal heterogeneity can be used to predict the malignant status of lymph node in colon cancer patients. Also, the number of lymph nodes near the colonic tumor should be considered in assessment of colon cancer lymph node involvement on CT. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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