A Meta-analysis of Outcome Studies of Autistic Adults: Quantifying Effect Size, Quality, and Meta-regression.

Longitudinal studies have generally reported poor outcomes in adulthood for the majority of individuals (c.50–60%) with autism. Several factors putatively predict outcome (e.g. IQ), but findings remain mixed. This paper presents an updated meta-analysis of autism outcome studies and extends previous...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 51; no. 9; pp. 3165 - 3180
Autores principales: Mason, David, Capp, Simone J., Stewart, Gavin R., Kempton, Matthew J., Glaser, Karen, Howlin, Patricia, Happé, Francesca
Formato: research tables/charts Journal Article
Publicado: Springer Nature Sep2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep2021
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      pub: Springer Nature
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        10.1007/s10803-020-04763-2
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        atl: A Meta-analysis of Outcome Studies of Autistic Adults: Quantifying Effect Size, Quality, and Meta-regression.
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          Mason, David
          Capp, Simone J.
          Stewart, Gavin R.
          Kempton, Matthew J.
          Glaser, Karen
          Howlin, Patricia
          Happé, Francesca
        affil: Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, Denmark Hill, SE5 8AF, London, UK
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        subj:
          Autism Spectrum Disorder Therapy
          Treatment Outcomes
          Human
          Meta Analysis
          Effect Size
          Regression
          Intelligence Evaluation
          Adult
          Adult: 19-44 years
      ab: Longitudinal studies have generally reported poor outcomes in adulthood for the majority of individuals (c.50–60%) with autism. Several factors putatively predict outcome (e.g. IQ), but findings remain mixed. This paper presents an updated meta-analysis of autism outcome studies and extends previous findings with additional analyses (including meta-regression). A total of 4088 records was screened and 18 studies, involving 1199 individuals, were included in the quantitative analysis. Estimated percentages indicated that 20.0% of participants were rated as having a good outcome, 26.6% a fair outcome, and 49.3% a poor outcome. Meta-regression indicated that lower IQ in adulthood was predictive of poor outcome; other meta-regression models did not survive correction for multiple comparisons. Overall, outcomes for autistic people are on average poor, and higher IQ appears to be protective against having a poor outcome. The limitations of current constructs of outcome are discussed.
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    language: English
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