Relevance of a Truncated PRESENILIN 2 Transcript to Alzheimer's Disease and Neurodegeneration.

Background: The PRESENILIN genes (PSEN1, PSEN2) encoding for their respective proteins have critical roles in many aspects of Alzheimer's disease (AD) pathogenesis. The PS2V transcript of PSEN2 encodes a truncated protein and is upregulated in AD brains; however, its relevance to AD and disease prog...

Descripción completa

Detalles Bibliográficos

Publicado en:	Journal of Alzheimer's Disease Vol. 80; no. 4; pp. 1479 - 1490
Autores principales:	Moussavi Nik, Seyyed Hani, Porter, Tenielle, Newman, Morgan, Bartlett, Benjamin, Khan, Imran, Sabale, Miheer, Eccles, Melissa, Woodfield, Amy, Groth, David, Dore, Vincent, Villemagne, Victor L., Masters, Colin L., Martins, Ralph N., Laws, Simon M., Lardelli, Michael, Verdile, Giuseppe
Formato:	research Journal Article
Publicado:	Sage Publications Inc. 2021
Acceso en línea:	Ver este registro en EBSCOhost