THREE-MODAL THEORY OF EARLY EMBRYO ASYMMETRIC CLEAVAGE DETERMINATION.
Developmental biology attempts to understand the most remarkable phenomenon of life, the process of embryogenesis, and trace back the common link between different groups of animals to analyze when and how the advantage of multicellularity and pluripotency first emerged. Gradual changes accumulated...
| Publicado en: | Cosmos & History Vol. 17; no. 1; pp. 299 - 326 |
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| Formato: | Artículo |
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Ashton & Rafferty
2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=hlh&AN=151823011&site=ehost-live header: @attributes: shortDbName: hlh uiTerm: 151823011 longDbName: Humanities International Complete uiTag: AN controlInfo: bkinfo: jinfo: jid: 18329101 78JL jtl: Cosmos & History issn: 18329101 maglogo: N pubinfo: dt: 2021 vid: 17 iid: 1 pid: 47219 pub: Ashton & Rafferty artinfo: ui: 151823011 ppf: 299 ppct: 27 formats: fmt: @attributes: type: P size: 1.6MB tig: atl: THREE-MODAL THEORY OF EARLY EMBRYO ASYMMETRIC CLEAVAGE DETERMINATION. aug: au: Liebich, Steve affil: Clarkson University, Biomolecular Science & Chemistry Department Clarkson 10 Postdam, NY 13676. su: Developmental biology Embryos Mammalian embryos Zygotes Set theory Mammal conservation sug: subj: Developmental biology Embryos Mammalian embryos Zygotes Set theory Mammal conservation keyword: Embryo cleavage Embryo development Origins of life ab: Developmental biology attempts to understand the most remarkable phenomenon of life, the process of embryogenesis, and trace back the common link between different groups of animals to analyze when and how the advantage of multicellularity and pluripotency first emerged. Gradual changes accumulated in animal genomes and the environmental influence on gene expression have led to the emergence of a higher complexity in body patterning and tissue diversity best seen in mammals. Although many questions have been answered, even more await to be elucidated. Presented is a developmental biology theory set into three main hypothetical claims that are collectively harmonizing at the molecular level of animal embryogenesis. Focusing on vertebrates and mammals, the three-modal theory of early embryo asymmetric cleavage determination attempts to explain how over 200 mammalian cell lines originate from a single zygote. Within the theory, biophysical interactions between first mammalian embryo cells are expected to develop a biochemical niche pivotal for further interblastomeric communication and asymmetric fate determination distribution, including those of the maternal origin. The theory builds on extensive research data from the past century and coherently fits in modern molecular understanding of a plethora of embryological processes. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y custom: Copyright of Cosmos & History is the property of Ashton & Rafferty and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. item: Cosmos & History holder: Ashton & Rafferty dt: @attributes: year: 2021 holdings: @attributes: islocal: N |
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