Relevance of fructose intake in adolescence for fatty liver indices in young adulthood.
Purpose: To examine the association between fructose intake in adolescence and fatty liver indices (hepatic steatosis index (HSI), fatty liver index (FLI)) in young adulthood. Methods: Overall, 246 participants of the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) study who...
| Publicado en: | European Journal of Nutrition Vol. 60; no. 6; pp. 3029 - 3042 |
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| Autores principales: | , , , , , , , , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Springer Nature
Sep2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=151838122&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 151838122 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14366207 CR0 jtl: European Journal of Nutrition issn: 14366207 maglogo: N pubinfo: dt: Sep2021 vid: 60 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 151838122 148179543 151838122 151838122 10.1007/s00394-020-02463-2 151838122 ppf: 3029 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Relevance of fructose intake in adolescence for fatty liver indices in young adulthood. aug: au: Perrar, Ines Buyken, Anette E. Penczynski, Katharina J. Remer, Thomas Kuhnle, Gunter G. Herder, Christian Roden, Michael Della Corte, Karen Nöthlings, Ute Alexy, Ute affil: Institute of Nutritional and Food Sciences, Nutritional Epidemiology, University of Bonn, DONALD Study, Heinstück 11, 44225, Dortmund, Germany sug: subj: Fructose Food Intake In Adolescence Nonalcoholic Fatty Liver Disease In Adulthood Human Dietary Sucrose Male Female Adolescence Young Adult Adult Descriptive Statistics Data Analysis Software Multivariate Analysis Linear Regression Biological Markers Confidence Intervals Body Mass Index Anthropometry Adolescent: 13-18 years Adult: 19-44 years Male Female ab: Purpose: To examine the association between fructose intake in adolescence and fatty liver indices (hepatic steatosis index (HSI), fatty liver index (FLI)) in young adulthood. Methods: Overall, 246 participants of the Dortmund Nutritional and Anthropometric Longitudinally Designed (DONALD) study who had a fasting blood sample in adulthood (18–36 years), at least two 3-day weighed dietary records for calculating fructose intakes and other fructose-containing sugars (total (TS), free (FS), added sugar (AS)) as well as two complete 24-h urine samples for calculating sugar excretion (fructose excretion (FE), fructose + sucrose excretion (FE + SE)) in adolescence (males: 9.5–16.5 years; females: 8.5–15.5 years) were analysed using multivariable linear regression analyses. Results: On the level of dietary intake, no prospective associations were observed between adolescent fructose intake and both adult fatty liver indices, whereas higher FS intakes were associated with lower levels of HSI (Ptrend = 0.02) and FLI (Ptrend = 0.03). On the urinary excretion level, however, a higher FE (Ptrend = 0.03) and FE + SE (Ptrend = 0.01) in adolescence were prospectively related to higher adult FLI values. No associations were observed between adolescent sugar excretion and adult HSI. Conclusion: The present study does not provide unambiguous support for a detrimental impact of adolescent fructose intake on adult liver health. Nonetheless, further examinations estimating exposure by means of urinary excretion as well as dietary intake levels appear warranted. pubtype: Academic Journal doctype: equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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