Cryptococcal infection presenting as soft tissue abscess and arthritis: Case report.
Rationale: Cryptococcal infection has been documented in immunocompromised patients. AIDS and renal transplant recipients account for majority of the cases. Most cases present with central nervous system or disseminated disease, with only few presenting soft tissue, bone, and joint manifestations.Pa...
| Published in: | Medicine Vol. 100; no. 28; pp. 1 - 6 |
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| Main Authors: | , , , , , |
| Format: | case study Journal Article |
| Published: |
Lippincott Williams & Wilkins
7/16/2021
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=152033059&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 152033059 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00257974 2S6 jtl: Medicine issn: 00257974 maglogo: N pubinfo: dt: 7/16/2021 vid: 100 iid: 28 pid: 433 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 152033059 152033059 NLM34260570 152033059 10.1097/MD.0000000000026656 NLM34260570 152033059 ppf: 1 ppct: 5 formats: tig: atl: Cryptococcal infection presenting as soft tissue abscess and arthritis: Case report. aug: au: Yong Jin Cho Song Iy Han Sung-Chul Lim Cho, Yong Jin Han, Song Iy Lim, Sung-Chul affil: Department of Orthopedic Surgery, College of Medicine, Chosun University, Gwangju, Korea. sug: subj: Abscess Microbiology Cryptococcosis Diagnosis Fluconazole Therapeutic Use Immunocompromised Host Physiology Kidney Transplantation Arthritis Physiopathology Cryptococcus Heterocyclic Compounds Therapeutic Use Abscess Drug Therapy Diagnosis, Differential Male Aged Female Arthritis Diagnosis Abscess Diagnosis Cryptococcosis Physiopathology Antifungal Agents Therapeutic Use Cryptococcosis Drug Therapy Middle Age Scales Arthritis Impact Measurement Scales Aged: 65+ years Middle Aged: 45-64 years Male Female ab: Rationale: Cryptococcal infection has been documented in immunocompromised patients. AIDS and renal transplant recipients account for majority of the cases. Most cases present with central nervous system or disseminated disease, with only few presenting soft tissue, bone, and joint manifestations.Patient Concerns: We present a case of soft tissue mass in a 66-year-old female renal transplant recipient and that of arthritis in a 64-year-old immunocompetent man who presented pseudogout arthropathy. Chest radiographies of both cases were negative. Biopsy revealed cryptococcal organisms. Blood culture or cerebrospinal fluid sampling indicated positive results for cryptococcal antigen.Diagnosis: Cryptococcus neoformans was recovered in the wound culture.Interventions: The patients received intravenous fluconazole and flucytosine, followed by oral fluconazole administration.Outcomes: Symptomatic improvements were achieved and no subsequent relapses were observed.Lessons: The authors experienced 2 cases of cryptococcosis with very unusual clinical presentation. Early clinical suspicion and serum cryptococcal antigen testing can help in rapid appropriate diagnosis in immunocompetent as well as immunocompromised patients even in the absence of pulmonary involvement. pubtype: Academic Journal doctype: case study Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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