NO-HYPE: a novel hydrodynamic phantom for the evaluation of MRI flow measurements.
Accurate and reproducible measurement of blood flow profile is very important in many clinical investigations for diagnosing cardiovascular disorders. Given that many factors could affect human circulation, and several parameters must be set to properly evaluate blood flows with phase-contrast techn...
| Published in: | Medical & Biological Engineering & Computing Vol. 59; no. 9; pp. 1889 - 1900 |
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| Main Authors: | , , , , , , |
| Format: | Journal Article |
| Published: |
Springer Nature
Sep2021
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=152044040&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 152044040 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Sep2021 vid: 59 iid: 9 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 152044040 151813088 152044040 NLM34365590 10.1007/s11517-021-02390-2 NLM34365590 152044040 ppf: 1889 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: NO-HYPE: a novel hydrodynamic phantom for the evaluation of MRI flow measurements. aug: au: Gadda, Giacomo Cocozza, Sirio Gambaccini, Mauro Taibi, Angelo Tedeschi, Enrico Zamboni, Paolo Palma, Giuseppe affil: Section of Ferrara, National Institute for Nuclear Physics (INFN), 44122, Ferrara, Italy sug: subj: Magnetic Resonance Imaging Physiochemical Phenomena Software Hemodynamics Phantoms, Imaging Scales Psychological Tests ab: Accurate and reproducible measurement of blood flow profile is very important in many clinical investigations for diagnosing cardiovascular disorders. Given that many factors could affect human circulation, and several parameters must be set to properly evaluate blood flows with phase-contrast techniques, we developed an MRI-compatible hydrodynamic phantom to simulate different physiological blood flows. The phantom included a programmable hydraulic pump connected to a series of pipes immersed in a solution mimicking human soft tissues, with a blood-mimicking fluid flowing in the pipes. The pump is able to shape and control the flow by driving a piston through a dedicated software. Periodic waveforms are used as input to the pump to move the fluid into the pipes, with synchronization of the MRI sequences to the flow waveforms. A dedicated software is used to extract and analyze flow data from magnitude and phase images. The match between the nominal and the measured flows was assessed, and the scope of phantom variables useful for a reliable calibration of an MRI system was accordingly defined. Results showed that the NO-HYPE phantom is a valuable tool for the assessment of MRI scanners and sequence design for the MR evaluation of blood flows. Overview of the NOvel HYdrodynamic Phantom for the Evaluation of MRI flow measurements (NO-HYPE). Left: internal of the CompuFlow 1000 MR pump unit. Right: Setting of the NO-HYPE before a MRI acquisition session. Soft tissue mimicking material is hosted in the central part of the phantom (light blue chamber). Glass pipes pass through the chamber carrying the blood mimicking fluid. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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