A Mobile Health Intervention to Increase Physical Activity in Pulmonary Arterial Hypertension.
Background: Supervised exercise training improves outcomes in patients with pulmonary arterial hypertension (PAH). The effect of an unsupervised activity intervention has not been tested.Research Question: Can a text-based mobile health intervention increase step counts in patients with PAH?Study De...
| Publicado en: | CHEST Vol. 160; no. 3; pp. 1042 - 1053 |
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| Autores principales: | , , , , , , , , , , , , , , , |
| Formato: | research randomized controlled trial Journal Article |
| Publicado: |
American College of Chest Physicians
Sep2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=152061235&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 152061235 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00123692 1G4 jtl: CHEST issn: 00123692 maglogo: N pubinfo: dt: Sep2021 vid: 160 iid: 3 pid: 2556 pub: American College of Chest Physicians place: Glenview, Illinois artinfo: ui: 152061235 152061235 NLM33878341 152061235 10.1016/j.chest.2021.04.012 NLM33878341 152061235 ppf: 1042 ppct: 11 formats: tig: atl: A Mobile Health Intervention to Increase Physical Activity in Pulmonary Arterial Hypertension. aug: au: Hemnes, Anna R. Silverman-Lloyd, Luke G. Huang, Shi MacKinnon, Grant Annis, Jeffrey Whitmore, Carolyn S. Mallugari, Ravinder Oggs, Rashundra N. Hekmat, Rezzan Shan, Rongzi Huynh, Pauline P. Yu, Chang Martin, Seth S. Blaha, Michael J. Brittain, Evan L. Silverman-Loyd, Luke affil: Division of Allergy Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN sug: subj: Telemetry Methods Adipose Tissue Pathology Quality of Life Telemedicine Methods Exercise Telemedicine Equipment and Supplies Ventricular Function, Right Telemetry Equipment and Supplies Single-Blind Studies Female Body Weights and Measures Male Middle Age Text Messaging Echocardiography Methods Human Comparative Studies Multicenter Studies Randomized Controlled Trials Evaluation Research Validation Studies Clinical Assessment Tools Scales Ferrans and Powers Quality of Life Index Exercise of Self-Care Agency Scale Middle Aged: 45-64 years Female Male ab: Background: Supervised exercise training improves outcomes in patients with pulmonary arterial hypertension (PAH). The effect of an unsupervised activity intervention has not been tested.Research Question: Can a text-based mobile health intervention increase step counts in patients with PAH?Study Design and Methods: We performed a randomized, parallel arm, single-blind clinical trial. We randomized patients to usual care or a text message-based intervention for 12 weeks. The intervention arm received three automated text messages per day with real-time step count updates and encouraging messages rooted in behavioral change theory. Individual step targets increased by 20% every 4 weeks. The primary end point was mean week 12 step counts. Secondary end points included the 6-min walk test, quality of life, right ventricular function, and body composition.Results: Among 42 randomized participants, the change in raw steps between baseline and week 12 was higher in the intervention group (1,409 steps [interquartile range, -32 to 2,220] vs -149 steps [interquartile range, -1,010 to 735]; P = .02), which persisted after adjustment for age, sex, baseline step counts, and functional class (model estimated difference, 1,250 steps; P = .03). The intervention arm took a higher average number of steps on all days between days 9 and 84 (P < .05, all days). There was no difference in week 12 six-minute walk distance. Analysis of secondary end points suggested improvements in the emPHasis-10 score (adjusted change, -4.2; P = .046), a reduction in visceral fat volume (adjusted change, -170 mL; P = .023), and nearly significant improvement in tricuspid annular plane systolic excursion (model estimated difference, 1.2 mm; P = .051).Interpretation: This study demonstrated the feasibility of an automated text message-based intervention to increase physical activity in patients with PAH. Additional studies are warranted to examine the effect of the intervention on clinical outcomes.Clinical Trial Registration: ClinicalTrials.gov; No. NCT03069716; URL: www.clinicaltrials.gov. pubtype: Academic Journal doctype: research randomized controlled trial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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