Clinical and microbiological evaluation of the efficacy of autoprobiotics in the combination treatment of chronic generalized periodontitis.
Combination treatment of patients with inflammatory periodontal diseases may be ineffective due to the variability of periodontal pathogens and the polyetiology of the disease. This disadvantage can be overcome by using highly antagonistic, enzymatic, and immunostimulating drugs, in addition to the...
| Published in: | Revista Latinoamericana de Hipertensión Vol. 16; no. 1; pp. 15 - 28 |
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| Main Authors: | , , , , |
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Revista Latinoamericana de Hipertension
2021
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| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=lth&AN=152115069&site=ehost-live header: @attributes: shortDbName: lth uiTerm: 152115069 longDbName: MedicLatina uiTag: AN controlInfo: bkinfo: jinfo: jid: 18564550 FICN jtl: Revista Latinoamericana de Hipertensión issn: 18564550 maglogo: N pubinfo: dt: 2021 vid: 16 iid: 1 pid: 81901 pub: Revista Latinoamericana de Hipertension artinfo: ui: 152115069 10.5281/zenodo.5102968 ppf: 15 ppct: 13 formats: fmt: @attributes: type: P size: 771KB tig: atl: Clinical and microbiological evaluation of the efficacy of autoprobiotics in the combination treatment of chronic generalized periodontitis. aug: au: Koroleva, Irina V. Mikhaylova, Ekaterina S. Zhukovskaia, Katerina S. Kraeva, Lyudmila A. Suvorov, Alexander N. affil: Saint Petersburg State University, St. Petersburg, Russia, 199034, Universitetskaya emb. 7-9, Federal State Budgetary Scientific Institution "Institute of Experimental Medicine», St. Petersburg, Russia, 197376, Academician Pavlov str., 12 Saint Petersburg State University, St. Petersburg, Russia, 199034, Universitetskaya emb. 7-9 Saint Petersburg State University, St. Petersburg, Russia, 199034, Universitetskaya emb. 7-9, S.M. Kirov Military Medical Academy, St. Petersburg, Russia, 194044, Academician Lebedev street lit. F Saint Petersburg Pasteur Institute, St. Petersburg, Russia, 197101, Saint Petersburg, Mira str., 14 Saint Petersburg State University, St. Petersburg, Russia, 199034, Universitetskaya emb. 7-9; Federal State Budgetary Scientific Institution "Institute of Experimental Medicine», St. Petersburg, Russia, 197376, Academician Pavlov str., 12 su: Tooth root planing Periodontitis Periodontal pockets Oral hygiene Probiotics Periodontal disease sug: subj: Tooth root planing Periodontitis Periodontal pockets Oral hygiene Probiotics Periodontal disease keyword: autoprobiotics chronic periodontitis microbiota periodontal pathogenes probiotic therapy probiotics autoprobióticos patógenos periodontales periodontitis crónica probióticos terapia probiótica ab: Combination treatment of patients with inflammatory periodontal diseases may be ineffective due to the variability of periodontal pathogens and the polyetiology of the disease. This disadvantage can be overcome by using highly antagonistic, enzymatic, and immunostimulating drugs, in addition to the main treatment. The objective of this study is to clinically and microbiologically evaluate the efficacy of autoprobiotics in the combination treatment of chronic generalized periodontitis. The presented study involved a survey of 37 patients aged 29 to 64 years with mild chronic generalized periodontitis. The patients were divided into three groups. Group I consisted of patients whose combination treatment included an S. salivarius-based autoprobiotic (subgroup 1 - patients who had their periodontal pockets irrigated with an autoprobiotic, subgroup 2 - patients who used oral baths with autoprobiotic). Group II consisted of patients who used a common S. salivarius-based probiotic in combination treatment (subgroup 1 - patients who had their periodontal pockets irrigated with a probiotic, subgroup 2 - patients who used oral baths with a probiotic). The control group consisted of patients with mild chronic generalized periodontitis, whose combination treatment consisted of professional oral hygiene and correction of individual hygiene. Microbiological examination of the content of periodontal pockets was carried out using PCR screening for periodontal pathogens, such as P. gingivalis, T. denticola, T. forsythia, P. intermedia. Based on the clinical and microbiological results of the study, the efficacy of an autoprobiotic and probiotic based on S. salivarius in the combination treatment of mild chronic generalized periodontitis was demonstrated. Etratamiento combinado de pacientes con enfermedades periodontales inflamatorias puede resultar ineficaz debido a la variabilidad de los patógenos periodontales y la polietiología de la enfermedad. Esta desventaja puede superarse mediante el uso de fármacos altamente antagonistas, enzimáticos e inmunoestimulantes, además del tratamiento principal. El objetivo de este estudio es evaluar clínica y microbiológicamente la eficacia de los autoprobióticos en el tratamiento combinado de la periodontitis crónica generalizada. El estudio presentado incluyó una encuesta de 37 pacientes de 29 a 64 años con periodontitis crónica generalizada leve. Los pacientes se dividieron en tres grupos. El grupo I consistió en pacientes cuyo tratamiento combinado incluía un autoprobiótico basado en S. salivarius (subgrupo 1 - pacientes que tenían sus bolsas periodontales irrigadas con un autoprobiótico, subgrupo 2 - pacientes que usaron baños orales con autoprobiótico). El grupo II consistió en pacientes que usaron un probiótico común a base de S. salivarius en tratamiento combinado (subgrupo 1 - pacientes que tenían sus bolsas periodontales irrigadas con un probiótico, subgrupo 2 - pacientes que usaron baños orales con un probiótico). El grupo control estuvo formado por pacientes con periodontitis crónica generalizada leve, cuyo tratamiento combinado consistió en higiene bucal profesional y corrección de la higiene individual. El examen microbiológico del contenido de las bolsas periodontales se llevó a cabo mediante el cribado por PCR de patógenos periodontales, como P. gingivalis, T. denticola, T. forsythia, P. intermedia. Con base en los resultados clínicos y microbiológicos del estudio, se demostró la eficacia de un autoprobiótico y un probiótico a base de S. salivarius en el tratamiento combinado de la periodontitis crónica generalizada leve. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: Y custom: Copyright of Revista Latinoamericana de Hipertensión is the property of Revista Latinoamericana de Hipertension and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. item: Revista Latinoamericana de Hipertensión holder: Revista Latinoamericana de Hipertension dt: @attributes: year: 2021 holdings: @attributes: islocal: N |
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