Predicting postoperative surgical site infection with administrative data: a random forests algorithm.

Background: Since primary data collection can be time-consuming and expensive, surgical site infections (SSIs) could ideally be monitored using routinely collected administrative data. We derived and internally validated efficient algorithms to identify SSIs within 30 days after surgery with health...

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Publicado en:BMC Medical Research Methodology Vol. 21; no. 1; pp. 1 - 12
Autores principales: Petrosyan, Yelena, Thavorn, Kednapa, Smith, Glenys, Maclure, Malcolm, Preston, Roanne, van Walravan, Carl, Forster, Alan J.
Formato: research Journal Article
Publicado: BioMed Central 8/28/2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 8/28/2021
      vid: 21
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      pub: BioMed Central
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        10.1186/s12874-021-01369-9
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        152168321
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        atl: Predicting postoperative surgical site infection with administrative data: a random forests algorithm.
      aug:
        au:
          Petrosyan, Yelena
          Thavorn, Kednapa
          Smith, Glenys
          Maclure, Malcolm
          Preston, Roanne
          van Walravan, Carl
          Forster, Alan J.
        affil: Clinical Epidemiology, Ottawa Hospital Research Institute, 1053 Carling Ave, K1Y 4E9, Ottawa, Ontario, Canada
      sug:
        subj:
          Algorithms
          Surgical Wound Infection Epidemiology
          Surgical Wound Infection Diagnosis
          Human
          Ontario
          Risk Factors
          Logistic Regression
          Comparative Studies
          Multicenter Studies
          Evaluation Research
          Validation Studies
          Social Support Index
          Ferrans and Powers Quality of Life Index
      ab: Background: Since primary data collection can be time-consuming and expensive, surgical site infections (SSIs) could ideally be monitored using routinely collected administrative data. We derived and internally validated efficient algorithms to identify SSIs within 30 days after surgery with health administrative data, using Machine Learning algorithms.Methods: All patients enrolled in the National Surgical Quality Improvement Program from the Ottawa Hospital were linked to administrative datasets in Ontario, Canada. Machine Learning approaches, including a Random Forests algorithm and the high-performance logistic regression, were used to derive parsimonious models to predict SSI status. Finally, a risk score methodology was used to transform the final models into the risk score system. The SSI risk models were validated in the validation datasets.Results: Of 14,351 patients, 795 (5.5%) had an SSI. First, separate predictive models were built for three distinct administrative datasets. The final model, including hospitalization diagnostic, physician diagnostic and procedure codes, demonstrated excellent discrimination (C statistics, 0.91, 95% CI, 0.90-0.92) and calibration (Hosmer-Lemeshow χ2 statistics, 4.531, p = 0.402).Conclusion: We demonstrated that health administrative data can be effectively used to identify SSIs. Machine learning algorithms have shown a high degree of accuracy in predicting postoperative SSIs and can integrate and utilize a large amount of administrative data. External validation of this model is required before it can be routinely used to identify SSIs.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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