The fragility of origin essentialism: Where mitochondrial 'replacement' meets the non‐identity problem.
Few discussions of the ethics of mitochondrial 'replacement' techniques have drawn significant ethical distinctions between the two approaches now legal in the U.K. However, Anthony Wrigley, Stephen Wilkinson and John Appleby have together argued that under some circumstances pronuclear transfer (PN...
| Publicado en: | Bioethics Vol. 35; no. 7; pp. 615 - 623 |
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| Formato: | Artículo |
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Wiley-Blackwell
Sep2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=152209173&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 152209173 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 02699702 6PJ jtl: Bioethics issn: 02699702 maglogo: Y pubinfo: dt: Sep2021 vid: 35 iid: 7 pid: 480 pub: Wiley-Blackwell artinfo: ui: 152209173 10.1111/bioe.12910 ppf: 615 ppct: 8 formats: tig: atl: The fragility of origin essentialism: Where mitochondrial 'replacement' meets the non‐identity problem. aug: su: United Kingdom Ovum donation Genetic engineering Human reproductive technology Philosophy Bioethics Chromosomes Mitochondrial pathology Germ cells Preimplantation genetic diagnosis Genetic techniques sug: subj: Ovum donation Genetic engineering Human reproductive technology Philosophy Bioethics United Kingdom Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology) Chromosomes Mitochondrial pathology Germ cells Preimplantation genetic diagnosis Genetic techniques keyword: chromosomal origin essentialism gametic essentialism maternal spindle transfer mitochondrial replacement therapy non‐identity problem origin essentialism pronuclear transfer chromosomal origin essentialism gametic essentialism maternal spindle transfer mitochondrial replacement therapy non‐identity problem origin essentialism pronuclear transfer ab: Few discussions of the ethics of mitochondrial 'replacement' techniques have drawn significant ethical distinctions between the two approaches now legal in the U.K. However, Anthony Wrigley, Stephen Wilkinson and John Appleby have together argued that under some circumstances pronuclear transfer (PNT) may be in better ethical standing than maternal spindle transfer (MST). They base their conclusion on what they allege to be different implications of the techniques with respect to non‐identity considerations, which they ground on a version of origin essentialism. I raise a series of problems for their argument, which have cautionary implications for invocations of origin essentialism that go beyond specialized debates regarding MST and PNT. I argue that (i) origin essentialism is a fragile foundation for non‐identity considerations; (ii) gametic essentialism, which Wrigley et al. believe licenses their claims, is more questionable than origin essentialism; (iii) gametic essentialism does not straightforwardly justify their conclusion; and (iv) their conclusion in fact relies on an especially dubious position that we can call chromosomal origin essentialism. No good reasons have yet been supplied to distinguish PNT from MST on ethical grounds, and one should be wary of basing claims with practical impact on fragile foundations relating to origin essentialism. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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