Dietary patterns associated with renal impairment in the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA).

Background: Dietary-based primary prevention guidelines for chronic kidney disease (CKD) treatment are lacking due to limited evidence. Single nutrient intake studies do not account for complex dietary interactions. We assessed associations between dietary patterns and renal function in the Northern...

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Publicado en:European Journal of Nutrition Vol. 60; no. 7; pp. 4045 - 4055
Autores principales: Paterson, Euan N., Neville, Charlotte E., Wallace, Sara M., Woodside, Jayne V., Kee, Frank, Young, Ian S., Cruise, Sharon, McGuinness, Bernadette, Maxwell, Alexander P., McKay, Gareth J.
Formato: research tables/charts Journal Article
Publicado: Springer Nature Oct2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2021
      vid: 60
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00394-021-02579-z
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        atl: Dietary patterns associated with renal impairment in the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA).
      aug:
        au:
          Paterson, Euan N.
          Neville, Charlotte E.
          Wallace, Sara M.
          Woodside, Jayne V.
          Kee, Frank
          Young, Ian S.
          Cruise, Sharon
          McGuinness, Bernadette
          Maxwell, Alexander P.
          McKay, Gareth J.
        affil: Centre for Public Health, Queen's University Belfast, Belfast, Northern Ireland
      sug:
        subj:
          Food Habits Northern Ireland
          Diet
          Kidney Diseases Northern Ireland
          Human
          Northern Ireland
          Prospective Studies
          Cross Sectional Studies
          Nonexperimental Studies
          Questionnaires
          Middle Age
          Aged
          Aged, 80 and Over
          Factor Analysis
          Glomerular Filtration Rate
          Creatinine Blood
          Cystatin C Blood
          Multivariate Analysis
          Regression
          Confidence Intervals
          Alcohol Drinking
          Coffee Adverse Effects
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
      ab: Background: Dietary-based primary prevention guidelines for chronic kidney disease (CKD) treatment are lacking due to limited evidence. Single nutrient intake studies do not account for complex dietary interactions. We assessed associations between dietary patterns and renal function in the Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA). Design: A cross-sectional observational study used NICOLA baseline dietary data collected between February 2014 and March 2016 via a food frequency questionnaire for 2590 participants aged ≥ 50 years. Principal component analysis identified a posteriori dietary patterns. Renal function was characterised by estimated glomerular filtration rate (eGFR) using serum creatinine and cystatin-C. Associations were assessed according to quintiles of dietary pattern adherence and multivariable regression analysis examined associations with eGFR. Results: Variation in three dietary patterns was significantly associated with eGFR. After adjustment for potential confounders, participants with least adherence to the 'healthy' dietary pattern 1 had a mean eGFR 3.4 ml/min/1.73m2 (95% confidence interval, [CI] − 5.0, − 1.7, p < 0.001) lower than the most adherent. Those with lowest adherence to the 'unhealthy' dietary pattern 2 had a mean eGFR 1.9 ml/min/1.73m2 (CI 0.2, 3.5, p = 0.03) higher than those with highest adherence. Participants with lowest adherence to dietary pattern 3, characterised by a high consumption of alcohol and coffee, had a mean eGFR 1.8 ml/min/1.73m2 (− 3.5, − 0.01, p = 0.05) lower than those with greatest adherence. Conclusions: Our findings identify independent associations between dietary patterns and eGFR. These findings can inform the development of diet-related primary prevention advice for CKD.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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