In vivo preliminary test of a new biparietal bidirectional bipolar radiofrequency magnetic coupling system.

Background: To test in vivo a new design prototype for radio frequency (RF) ablation. Methods: A prototype based on a concept of endo‐epicardial biparietal bipolar RF ablation with the atrial tissue interposed and consisting of two specular endocardial‐epicardial catheters was tested in four pigs (8...

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Publicado en:Pacing & Clinical Electrophysiology Vol. 44; no. 9; pp. 1585 - 1593
Autores principales: Matteucci, Francesco, La Meir, Mark, Maesen, Bart, Chierchia, Gian‐Battista, De Asmundis, Carlo, Gelsomino, Sandro
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell Sep2021
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Pacing & Clinical Electrophysiology
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      dt: Sep2021
      vid: 44
      iid: 9
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/pace.14320
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        atl: In vivo preliminary test of a new biparietal bidirectional bipolar radiofrequency magnetic coupling system.
      aug:
        au:
          Matteucci, Francesco
          La Meir, Mark
          Maesen, Bart
          Chierchia, Gian‐Battista
          De Asmundis, Carlo
          Gelsomino, Sandro
        affil: Maastricht University, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands
      sug:
        subj:
          Radiofrequency Ablation
          Catheter Ablation
          Endocardium
          Animal Studies
          Swine
          In Vivo Studies
          Heart Atrium, Left
          Descriptive Statistics
          Atrial Fibrillation Surgery
          Treatment Outcomes
      ab: Background: To test in vivo a new design prototype for radio frequency (RF) ablation. Methods: A prototype based on a concept of endo‐epicardial biparietal bipolar RF ablation with the atrial tissue interposed and consisting of two specular endocardial‐epicardial catheters was tested in four pigs (80±5 kg). The endocardial catheter was introduced into the left atrium through the left atrial appendage on the beating heart. The epicardial counterpart was placed manually on the atrial epicardial surface. The coupling of the two catheters was achieved using a neodymium magnet around the gold plate electrode, and RF was applied to the interposed tissue. The hearts were excised, and the lesions were examined using morphometric evaluation. Results: The RF application resulted in transmural lesions in all of the four animals tested. In these animals the maximum endocardial width (Wendo) was 6.34 ± 0.25, 6.54 ± 0.33, 6.36 ± 0.57, and 6.49 ± 0.96 mm. The pericardial width (Wepi) was similar: 6.37 ± 0.47, 6.58 ± 0.32, 6.35 ± 0.56 and 6.53 ± 0.94 mm. The lesion area was 924.78, 949.25, 944.25, and 926.05 mm2, and the lesion volume was 92.47, 94.92, 94.42, and 92.60 mm3, respectively. Conclusions: The idea of an endocardial‐epicardial bidirectional biparietal bipolar radiofrequency tool such that the atrial tissue is fully interposed between the two RF poles might be promising for future clinical applications. Further research is warranted.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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