A phase I study of a PARP1-targeted topical fluorophore for the detection of oral cancer.

Background: Visual inspection and biopsy is the current standard of care for oral cancer diagnosis, but is subject to misinterpretation and consequently to misdiagnosis. Topically applied PARPi-FL is a molecularly specific, fluorescent contrast-based approach that may fulfill the unmet need for a si...

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Publicado en:European Journal of Nuclear Medicine & Molecular Imaging Vol. 48; no. 11; pp. 3618 - 3631
Autores principales: Demétrio de Souza França, Paula, Kossatz, Susanne, Brand, Christian, Karassawa Zanoni, Daniella, Roberts, Sheryl, Guru, Navjot, Adilbay, Dauren, Mauguen, Audrey, Valero Mayor, Cristina, Weber, Wolfgang A., Schöder, Heiko, Ghossein, Ronald A., Ganly, Ian, Patel, Snehal G., Reiner, Thomas
Formato: Journal Article
Publicado: Springer Nature Oct2021
Acceso en línea:Ver este registro en EBSCOhost