2D and 3D numerical models to evaluate trabecular bone damage.

The comprehension of trabecular bone damage processes could be a crucial hint for understanding how bone damage starts and propagates. Currently, different approaches to bone damage identification could be followed. Clinical approaches start from dual X-ray absorptiometry (DXA) technique that can ev...

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Publicado en:Medical & Biological Engineering & Computing Vol. 59; no. 10; pp. 2139 - 2153
Autores principales: Buccino, Federica, Colombo, Chiara, Duarte, Daniel Hernando Lozano, Rinaudo, Luca, Ulivieri, Fabio Massimo, Vergani, Laura Maria
Formato: Journal Article
Publicado: Springer Nature Oct2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2021
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      pub: Springer Nature
      place: New York, New York
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        atl: 2D and 3D numerical models to evaluate trabecular bone damage.
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        au:
          Buccino, Federica
          Colombo, Chiara
          Duarte, Daniel Hernando Lozano
          Rinaudo, Luca
          Ulivieri, Fabio Massimo
          Vergani, Laura Maria
        affil: Department of Mechanical Engineering, Politecnico Di Milano, Via La Masa 1, 20156, Milan, Italy
      sug:
        subj:
          Fractures
          Tomography, X-Ray Computed
          Swine
          Absorptiometry, Photon
          Animals
          Bone Density
          Language Tests
          Clinical Assessment Tools
          Scales
      ab: The comprehension of trabecular bone damage processes could be a crucial hint for understanding how bone damage starts and propagates. Currently, different approaches to bone damage identification could be followed. Clinical approaches start from dual X-ray absorptiometry (DXA) technique that can evaluate bone mineral density (BMD), an indirect indicator of fracture risk. DXA is, in fact, a two-dimensional technology, and BMD alone is not able to predict the effective risk of fractures. First attempts in overcoming this issue have been performed with finite element (FE) methods, combined with the use of three-dimensional high-resolution micro-computed tomographic images. The purpose of this work is to evaluate damage initiation and propagation in trabecular vertebral porcine samples using 2D linear-elastic FE models from DXA images and 3D linear FE models from micro-CT images. Results show that computed values of strains with 2D and 3D approaches (e.g., the minimum principal strain) are of the same order of magnitude. 2D DXA-based models still remain a powerful tool for a preliminary screening of trabecular regions that are prone to fracture, while from 3D micro-CT-based models, it is possible to reach details that permit the localization of the most strained trabecula.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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