A Coarse-to-Fine Framework for Automated Knee Bone and Cartilage Segmentation Data from the Osteoarthritis Initiative.

Knee osteoarthritis (OA) is a degenerative joint disease that is prevalent in advancing age. The pathology of OA disease is still unclear, and there are no effective interventions that can completely alter the OA disease process. Magnetic resonance (MR) image evaluation is sensitive for depicting ea...

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Publicado en:Journal of Digital Imaging Vol. 34; no. 4; pp. 833 - 841
Autores principales: Deng, Yang, You, Lei, Wang, Yanfei, Zhou, Xiaobo
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Aug2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2021
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-021-00464-z
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        atl: A Coarse-to-Fine Framework for Automated Knee Bone and Cartilage Segmentation Data from the Osteoarthritis Initiative.
      aug:
        au:
          Deng, Yang
          You, Lei
          Wang, Yanfei
          Zhou, Xiaobo
        affil: School of Biomedical Informatics, The University of Texas Health Science Center At Houston, 77030, Houston, TX, USA
      sug:
        subj:
          Osteoarthritis, Knee
          Magnetic Resonance Imaging
          Deep Learning
          Human
          Male
          Female
          Middle Age
          Aged
          Descriptive Statistics
          Cartilage, Articular
          Patella
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Knee osteoarthritis (OA) is a degenerative joint disease that is prevalent in advancing age. The pathology of OA disease is still unclear, and there are no effective interventions that can completely alter the OA disease process. Magnetic resonance (MR) image evaluation is sensitive for depicting early changes of knee OA, and therefore important for early clinical intervention for relieving the symptom. Automated cartilage segmentation based on MR images is a vital step in experimental longitudinal studies to follow-up the patients and prospectively define a new quantitative marker from OA progression. In this paper, we develop a deep learning–based coarse-to-fine approach for automated knee bone, cartilage, and meniscus segmentation with high computational efficiency. The proposed method is evaluated using two-fold cross-validation on 507 MR volumes (81,120 slices) with OA from the Osteoarthritis Initiative (OAI)1 dataset. The mean dice similarity coefficients (DSCs) of femoral bone (FB), tibial bone (TB), femoral cartilage (FC), and tibial cartilage (TC) separately are 99.1%, 98.2%, 90.9%, and 85.8%. The time of segmenting each patient is 12 s, which is fast enough to be used in clinical practice. Our proposed approach may provide an automated toolkit to help computer-aided quantitative analyses of OA images.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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