Brain MRI Deep Learning and Bayesian Inference System Augments Radiology Resident Performance.

Automated quantitative and probabilistic medical image analysis has the potential to improve the accuracy and efficiency of the radiology workflow. We sought to determine whether AI systems for brain MRI diagnosis could be used as a clinical decision support tool to augment radiologist performance....

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Publicado en:Journal of Digital Imaging Vol. 34; no. 4; pp. 1049 - 1059
Autores principales: Rudie, Jeffrey D., Duda, Jeffrey, Duong, Michael Tran, Chen, Po-Hao, Xie, Long, Kurtz, Robert, Ware, Jeffrey B., Choi, Joshua, Mattay, Raghav R., Botzolakis, Emmanuel J., Gee, James C., Bryan, R. Nick, Cook, Tessa S., Mohan, Suyash, Nasrallah, Ilya M., Rauschecker, Andreas M.
Formato: pictorial research tables/charts Journal Article
Publicado: Springer Nature Aug2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2021
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      pub: Springer Nature
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        atl: Brain MRI Deep Learning and Bayesian Inference System Augments Radiology Resident Performance.
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          Rudie, Jeffrey D.
          Duda, Jeffrey
          Duong, Michael Tran
          Chen, Po-Hao
          Xie, Long
          Kurtz, Robert
          Ware, Jeffrey B.
          Choi, Joshua
          Mattay, Raghav R.
          Botzolakis, Emmanuel J.
          Gee, James C.
          Bryan, R. Nick
          Cook, Tessa S.
          Mohan, Suyash
          Nasrallah, Ilya M.
          Rauschecker, Andreas M.
        affil: Department of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
      sug:
        subj:
          Brain
          Magnetic Resonance Imaging
          Deep Learning
          Probability
          Decision Support Systems, Clinical
          Specialties, Medical
          Interns and Residents
          Clinical Competence
          Human
          Female
          Male
          Adult
          Middle Age
          Aged
          Descriptive Statistics
          Neural Networks (Computer)
          Neuroradiography
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
          Male
      ab: Automated quantitative and probabilistic medical image analysis has the potential to improve the accuracy and efficiency of the radiology workflow. We sought to determine whether AI systems for brain MRI diagnosis could be used as a clinical decision support tool to augment radiologist performance. We utilized previously developed AI systems that combine convolutional neural networks and expert-derived Bayesian networks to distinguish among 50 diagnostic entities on multimodal brain MRIs. We tested whether these systems could augment radiologist performance through an interactive clinical decision support tool known as Adaptive Radiology Interpretation and Education System (ARIES) in 194 test cases. Four radiology residents and three academic neuroradiologists viewed half of the cases unassisted and half with the results of the AI system displayed on ARIES. Diagnostic accuracy of radiologists for top diagnosis (TDx) and top three differential diagnosis (T3DDx) was compared with and without ARIES. Radiology resident performance was significantly better with ARIES for both TDx (55% vs 30%; P <.001) and T3DDx (79% vs 52%; P = 0.002), with the largest improvement for rare diseases (39% increase for T3DDx; P < 0.001). There was no significant difference between attending performance with and without ARIES for TDx (72% vs 69%; P = 0.48) or T3DDx (86% vs 89%; P = 0.39). These findings suggest that a hybrid deep learning and Bayesian inference clinical decision support system has the potential to augment diagnostic accuracy of non-specialists to approach the level of subspecialists for a large array of diseases on brain MRI.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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