Acute Cardiac Alterations Among Young Adults With Sars-CoV-2...2021 ACSM Annual Meeting & World Congresses [Virtual], June 1-5, 2021.

BACKGROUND: The novel SARS-CoV-2 virus inflicts far-reaching health decrements, both directly and through secondary inflammatory stimulation. To date, there is little information regarding the effects of COVID-19 on the heart after infection, especially among young healthy adults. PURPOSE: We sought...

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Publicado en:Medicine & Science in Sports & Exercise Vol. 53; no. 8S; p. 70
Autores principales: Osada, Sophie S., Szeghy, Rachel E., Province, Valesha M., Koontz, Laurel K., Bobo, Landry K., Stute, Nina L., Augenreich, Marc A., Putnam, Andrew J., Stickford, Jonathon L., Stickford, Abigail S. L., Ratchford, Stephen M.
Formato: abstract proceedings research Journal Article
Publicado: Lippincott Williams & Wilkins 2021 Supplement
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2021 Supplement
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        10.1249/01.mss.0000759900.08616.70
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        atl: Acute Cardiac Alterations Among Young Adults With Sars-CoV-2...2021 ACSM Annual Meeting & World Congresses [Virtual], June 1-5, 2021.
      aug:
        au:
          Osada, Sophie S.
          Szeghy, Rachel E.
          Province, Valesha M.
          Koontz, Laurel K.
          Bobo, Landry K.
          Stute, Nina L.
          Augenreich, Marc A.
          Putnam, Andrew J.
          Stickford, Jonathon L.
          Stickford, Abigail S. L.
          Ratchford, Stephen M.
        affil: Appalachian State University, Boone, NC
      sug:
        subj:
          SARS-CoV-2 In Adulthood
          Cardiovascular System Physiology
          COVID-19
          Congresses and Conferences
          Young Adult
      ab: BACKGROUND: The novel SARS-CoV-2 virus inflicts far-reaching health decrements, both directly and through secondary inflammatory stimulation. To date, there is little information regarding the effects of COVID-19 on the heart after infection, especially among young healthy adults. PURPOSE: We sought to determine whether contracting SARS-CoV-2 affects cardiac function in young, otherwise healthy adults, weeks after testing positive for SARS-CoV-2. METHODS: Transthoracic echocardiography was performed on 14 subjects with SARS-CoV-2 (8F/6M, 21±1y, 24±3 kg⋅m-1) who tested positive 3-4 weeks prior to study test date. A parasternal long-axis view was utilized to measure septal and left ventricular posterior wall thickness, left ventricular volume, and left ventricular outflow tract dimensions. A four-chamber view was utilized to measure mitral valve function, diastolic function, end diastolic and systolic volume, and ejection fraction. Z-tests were performed to determine if these values were significantly different from sex- and age-matched normative values with significance set at p<0.01 (mean±SD). RESULTS: The left ventricular diastolic mass and index were found to be higher in both female (Mass: 173±52g, Index: 95±18g/m^2) and male (Mass: 214±34g, Index: 110±15g/m^2) subjects with SARS-CoV-2 compared to reference values (Female Mass: 104±28g, Female Index: 62±15g/m^2, Male Mass: 143±39g, Male Index: 72±18g/m^2) (p<0.01). Septal wall e' was elevated in both female (0.16±0.05m/s) and male (0.15±0.01m/s) subjects compared to reference values (Female: 0.12±0.2m/s, Male: 0.12±0.03m/s) (p<0.01). CONCLUSIONS: The current findings suggest subclinical alterations to the myocardium of young adults who have recently contracted SARS-CoV-2. These results warrant further review to examine whether low-level myocardial inflammation or interstitial edema may be present and whether persistent systemic vascular resistance may be causing left ventricular dysfunction and wall thickening.
      pubtype: Academic Journal
      doctype:
        abstract
        proceedings
        research
        Journal Article
      ougenre: Article
    language: English
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