Effects of circadian variation, lifestyle and environment on hematological parameters: A narrative review.

The complete blood count (CBC) is the most widely prescribed laboratory test. It plays a key role in screening, diagnosing, and monitoring a variety of medical disorders. Preanalytical and analytical variables are responsible for more than 50% of laboratory errors that may lead to spurious CBC resul...

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Publicado en:International Journal of Laboratory Hematology Vol. 43; no. 5; pp. 917 - 927
Autores principales: Feriel, Joffrey, Tchipeva, Draga, Depasse, François
Formato: review tables/charts Journal Article
Publicado: Wiley-Blackwell Oct2021
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Oct2021
      vid: 43
      iid: 5
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/ijlh.13590
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        atl: Effects of circadian variation, lifestyle and environment on hematological parameters: A narrative review.
      aug:
        au:
          Feriel, Joffrey
          Tchipeva, Draga
          Depasse, François
        affil: Diagnostica Stago, Asnieres Sur Seine, France
      sug:
        subj:
          Circadian Rhythm Physiology
          Life Style Changes
          Environment
          Blood Cell Count Psychosocial Factors
          Biological Markers
          Hematology
      ab: The complete blood count (CBC) is the most widely prescribed laboratory test. It plays a key role in screening, diagnosing, and monitoring a variety of medical disorders. Preanalytical and analytical variables are responsible for more than 50% of laboratory errors that may lead to spurious CBC results. The effects of blood sampling, transport, storage, and analytical errors on hematological parameters have been well described. Circadian variation and changes in lifestyle and environment can also affect blood cells. It has been extensively studied in the past, but highly variable methodology and the presence of confounding factors have provided scattered and inconsistent results. We have investigated the literature to define the impact of circadian variation, modification of the sleep‐wake cycle, acute and chronic exercise, eating habits, alcohol, tobacco, drugs of abuse, high‐altitude, heat/cold exposure, and air pollution on CBC results. The affected cell type along with the intensity and duration of changes are detailed for each condition. We aim at providing a comprehensive overview of which situations may induce clinically significant changes and have to be taken into account by healthcare professionals before considering a hematological parameter as pathological and requesting complementary tests.
      pubtype: Academic Journal
      doctype:
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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