Introduction to Artificial Intelligence and Machine Learning for Pathology.

* Context.--Recent developments in machine learning have stimulated intense interest in software that may augment or replace human experts. Machine learning may impact pathology practice by offering new capabilities in analysis, interpretation, and outcomes prediction using images and other data. Th...

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Published in:Archives of Pathology & Laboratory Medicine Vol. 145; no. 10; pp. 1228 - 1255
Main Authors: Harrison Jr., James H., Gilbertson, John R., Hanna, Matthew G., Olson, Niels H., Seheult, Jansen N., Sorace, James M., Stram, Michelle N.
Format: pictorial review tables/charts Journal Article
Published: College of American Pathologists Oct2021
Online Access:View this record in EBSCOhost
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      dt: Oct2021
      vid: 145
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      pub: College of American Pathologists
      place: Northfield, Illinois
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        atl: Introduction to Artificial Intelligence and Machine Learning for Pathology.
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        au:
          Harrison Jr., James H.
          Gilbertson, John R.
          Hanna, Matthew G.
          Olson, Niels H.
          Seheult, Jansen N.
          Sorace, James M.
          Stram, Michelle N.
        affil: Department of Pathology, University of Virginia School of Medicine, Charlottesville
      sug:
        subj:
          Medical Practice
          Machine Learning
          Pathologists Education
          Pathology, Clinical
          Algorithms
          Models, Statistical
          Productivity Evaluation
          Professional Role
          Technology
      ab: * Context.--Recent developments in machine learning have stimulated intense interest in software that may augment or replace human experts. Machine learning may impact pathology practice by offering new capabilities in analysis, interpretation, and outcomes prediction using images and other data. The principles of operation and management of machine learning systems are unfamiliar to pathologists, who anticipate a need for additional education to be effective as expert users and managers of the new tools. Objective.--To provide a background on machine learning for practicing pathologists, including an overview of algorithms, model development, and performance evaluation; to examine the current status of machine learning in pathology and consider possible roles and requirements for pathologists in local deployment and management of machine learning systems; and to highlight existing challenges and gaps in deployment methodology and regulation. Data Sources.--Sources include the biomedical and engineering literature, white papers from professional organizations, government reports, electronic resources, and authors' experience in machine learning. References were chosen when possible for accessibility to practicing pathologists without specialized training in mathematics, statistics, or software development. Conclusions.--Machine learning offers an array of techniques that in recent published results show substantial promise. Data suggest that human experts working with machine learning tools outperform humans or machines separately, but the optimal form for this combination in pathology has not been established. Significant questions related to the generalizability of machine learning systems, local site verification, and performance monitoring remain to be resolved before a consensus on best practices and a regulatory environment can be established.
      pubtype: Academic Journal
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        pictorial
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      ougenre: Article
    language: English
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