Distributed learning: a reliable privacy-preserving strategy to change multicenter collaborations using AI.

Purpose: The present scoping review aims to assess the non-inferiority of distributed learning over centrally and locally trained machine learning (ML) models in medical applications. Methods: We performed a literature search using the term "distributed learning" OR "federated learning" in the PubMe...

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Publicado en:European Journal of Nuclear Medicine & Molecular Imaging Vol. 48; no. 12; pp. 3791 - 3805
Autores principales: Kirienko, Margarita, Sollini, Martina, Ninatti, Gaia, Loiacono, Daniele, Giacomello, Edoardo, Gozzi, Noemi, Amigoni, Francesco, Mainardi, Luca, Lanzi, Pier Luca, Chiti, Arturo
Formato: Journal Article
Publicado: Springer Nature Nov2021
Acceso en línea:Ver este registro en EBSCOhost
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        10.1007/s00259-021-05339-7
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          Kirienko, Margarita
          Sollini, Martina
          Ninatti, Gaia
          Loiacono, Daniele
          Giacomello, Edoardo
          Gozzi, Noemi
          Amigoni, Francesco
          Mainardi, Luca
          Lanzi, Pier Luca
          Chiti, Arturo
        affil: Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
      sug:
      ab: Purpose: The present scoping review aims to assess the non-inferiority of distributed learning over centrally and locally trained machine learning (ML) models in medical applications. Methods: We performed a literature search using the term "distributed learning" OR "federated learning" in the PubMed/MEDLINE and EMBASE databases. No start date limit was used, and the search was extended until July 21, 2020. We excluded articles outside the field of interest; guidelines or expert opinion, review articles and meta-analyses, editorials, letters or commentaries, and conference abstracts; articles not in the English language; and studies not using medical data. Selected studies were classified and analysed according to their aim(s). Results: We included 26 papers aimed at predicting one or more outcomes: namely risk, diagnosis, prognosis, and treatment side effect/adverse drug reaction. Distributed learning was compared to centralized or localized training in 21/26 and 14/26 selected papers, respectively. Regardless of the aim, the type of input, the method, and the classifier, distributed learning performed close to centralized training, but two experiments focused on diagnosis. In all but 2 cases, distributed learning outperformed locally trained models. Conclusion: Distributed learning resulted in a reliable strategy for model development; indeed, it performed equally to models trained on centralized datasets. Sensitive data can get preserved since they are not shared for model development. Distributed learning constitutes a promising solution for ML-based research and practice since large, diverse datasets are crucial for success.
      pubtype: Academic Journal
      doctype: Journal Article
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    language: English
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