Transpathology: molecular imaging-based pathology.
Pathology is the medical specialty concerned with the study of the disease nature and causes, playing a key role in bridging basic researches and clinical medicine. In the course of development, pathology has significantly expanded our understanding of disease, and exerted enormous impact on the man...
| Published in: | European Journal of Nuclear Medicine & Molecular Imaging Vol. 48; no. 8; pp. 2338 - 2351 |
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| Main Authors: | , , , , , , , , , , |
| Format: | Journal Article |
| Published: |
Springer Nature
Jul2021
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=152814341&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 152814341 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 16197070 NPC jtl: European Journal of Nuclear Medicine & Molecular Imaging issn: 16197070 maglogo: N pubinfo: dt: Jul2021 vid: 48 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 152814341 148697032 10.1007/s00259-021-05234-1 152814341 ppf: 2338 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Transpathology: molecular imaging-based pathology. aug: au: Tian, Mei He, Xuexin Jin, Chentao He, Xiao Wu, Shuang Zhou, Rui Zhang, Xiaohui Zhang, Kai Gu, Weizhong Wang, Jing Zhang, Hong affil: Department of Nuclear Medicine and PET Center, The Second Affiliated Hospital of Zhejiang University School of Medicine, 88 Jiefang Road, 310009, Hangzhou, Zhejiang, China sug: ab: Pathology is the medical specialty concerned with the study of the disease nature and causes, playing a key role in bridging basic researches and clinical medicine. In the course of development, pathology has significantly expanded our understanding of disease, and exerted enormous impact on the management of patients. However, challenges facing pathology, the inherent invasiveness of pathological practice and the persistent concerns on the sample representativeness, constitute its limitations. Molecular imaging is a noninvasive technique to visualize, characterize, and measure biological processes at the molecular level in living subjects. With the continuous development of equipment and probes, molecular imaging has enabled an increasingly precise evaluation of pathophysiological changes. A new pathophysiology visualization system based on molecular imaging is forming and shows the great potential to reform the pathological practice. Several improvements in "trans-," including trans-scale, transparency, and translation, would be driven by this new kind of pathological practice. Pathological changes could be evaluated in a trans-scale imaging mode; tissues could be transparentized to better present the underlying pathophysiological information; and the translational processes of basic research to the clinical practice would be better facilitated. Thus, transpathology would greatly facilitate in deciphering the pathophysiological events in a multiscale perspective, and supporting the precision medicine in the future. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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