| Sumario: | The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's association workgroups on diagnostic guidelines for Alzheimer's disease. Amyloid-imaging does not allow for differentiation between distinct amyloid-positive disorders, and positive amyloid scans are found in about one third of cognitively unimpaired elderly with yet unknown clinical relevance [[11]]. This article is part of the Topical Collection on Neurology In 1984, consensual criteria for Alzheimer's disease (AD) were published, which were fully based on symptoms as tracked by clinical and neuropsychological examinations [[1]]. From there, an amyloid-PET scan could be proposed only in cases who do not show an FDG-PET pattern typical for a specific diagnosis, if atypical AD is possible or if the amyloid status is required.
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