Quality of life outcomes in cryoablation of atrial fibrillation–A literature review.
Background: Cryoballoon ablation (CRYO) for pulmonary vein isolation (PVI) in atrial fibrillation (AF) has become an established treatment option as alternative for radiofrequency catheter ablation (RFCA). As symptom relief is still the main indication for PVI, quality of life (QoL) is a key outcome...
| Publicado en: | Pacing & Clinical Electrophysiology Vol. 44; no. 10; pp. 1756 - 1769 |
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| Autores principales: | , , , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Oct2021
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=152842268&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 152842268 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01478389 4F8 jtl: Pacing & Clinical Electrophysiology issn: 01478389 maglogo: Y pubinfo: dt: Oct2021 vid: 44 iid: 10 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 152842268 152064581 152842268 152842268 10.1111/pace.14341 152842268 ppf: 1756 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Quality of life outcomes in cryoablation of atrial fibrillation–A literature review. aug: au: Vandenberk, Bert Lauwers, Laurens Robyns, Tomas Garweg, Christophe Willems, Rik Ector, Joris Haemers, Peter affil: Department of Cardiology, University Hospitals Leuven, Leuven, Belgium sug: subj: Atrial Fibrillation Surgery Cryosurgery Methods Pulmonary Veins Surgery Quality of Life Evaluation Treatment Outcomes Evaluation Human Systematic Review PubMed Cochrane Library Cardiac Patients Descriptive Statistics Data Analysis Software ab: Background: Cryoballoon ablation (CRYO) for pulmonary vein isolation (PVI) in atrial fibrillation (AF) has become an established treatment option as alternative for radiofrequency catheter ablation (RFCA). As symptom relief is still the main indication for PVI, quality of life (QoL) is a key outcome parameter. This review summarizes the evidence about the evolution of QoL after CRYO. Methods: A search for clinical studies reporting QoL outcomes after CRYO was performed on PUBMED and COCHRANE. A total of 506 publications were screened and 10 studies met the in‐ and exclusion criteria. Results: All studies considered QoL as a secondary endpoint and reported significant improvement in QoL between baseline and 12 months follow‐up, independent of the QoL instruments used. The effect size of CRYO on QoL was comparable between studies and present in both paroxysmal and persistent AF. Direct comparison between CRYO and RFCA was limited to two studies, there was no difference between ablation modalities after 12 months FU. Two studies in paroxysmal AF reported outcome beyond 12 months follow‐up and QoL improvement was maintained up to 36 months after ablation. There were no long‐term data available for persistent AF. Conclusion: CRYO of AF significantly improves QoL. The scarce amount of data with direct comparison between subgroups limits further exploration. Assessment of QoL should be considered a primary outcome parameter in future trials with long‐term follow‐up. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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